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[HTML][HTML] Global reach of ageism on older persons' health: A systematic review
Objective Although there is anecdotal evidence of ageism occurring at both the structural
level (in which societal institutions reinforce systematic bias against older persons) and …
level (in which societal institutions reinforce systematic bias against older persons) and …
Brief introduction of medical database and data mining technology in big data era
Data mining technology can search for potentially valuable knowledge from a large amount
of data, mainly divided into data preparation and data mining, and expression and analysis …
of data, mainly divided into data preparation and data mining, and expression and analysis …
Estimating the prevalence of dementia and mild cognitive impairment in the US: the 2016 health and retirement study harmonized cognitive assessment protocol …
Importance Nationally representative data are critical for understanding the causes, costs,
and outcomes associated with dementia and mild cognitive impairment (MCI) in the US and …
and outcomes associated with dementia and mild cognitive impairment (MCI) in the US and …
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome …
sample of~ 3 million individuals and identify 3,952 approximately uncorrelated genome …
Map** genomic loci implicates genes and synaptic biology in schizophrenia
Schizophrenia has a heritability of 60–80%, much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …
Changes in frailty and incident cardiovascular disease in three prospective cohorts
D He, Z Wang, J Li, K Yu, Y He, X He, Y Liu… - European heart …, 2024 - academic.oup.com
Abstract Background and Aims Previous studies found that frailty was an important risk factor
for cardiovascular disease (CVD). However, previous studies only focused on baseline …
for cardiovascular disease (CVD). However, previous studies only focused on baseline …
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
Tobacco and alcohol use are leading causes of mortality that influence risk for many
complex diseases and disorders. They are heritable, and etiologically related, behaviors that …
complex diseases and disorders. They are heritable, and etiologically related, behaviors that …
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Here we conducted a large-scale genetic association analysis of educational attainment in a
sample of approximately 1.1 million individuals and identify 1,271 independent genome …
sample of approximately 1.1 million individuals and identify 1,271 independent genome …
Comparison of particulate air pollution from different emission sources and incident dementia in the US
Importance Emerging evidence indicates that exposure to fine particulate matter (PM 2.5) air
pollution may increase dementia risk in older adults. Although this evidence suggests …
pollution may increase dementia risk in older adults. Although this evidence suggests …
Map** genomic loci prioritises genes and implicates synaptic biology in schizophrenia
Schizophrenia Working Group of the Psychiatric … - MedRxiv, 2020 - medrxiv.org
Schizophrenia is a psychiatric disorder whose pathophysiology is largely unknown. It has a
heritability of 60-80%, much of which is attributable to common risk alleles, suggesting …
heritability of 60-80%, much of which is attributable to common risk alleles, suggesting …