Low intensity, non-noxious, stimulation of cutaneous somatosensory nerves has been
shown to trigger oxytocin release and is associated with increased social motivation, plus …

An accumulating body of evidence suggests that the hypothalamic neuropeptide oxytocin
(OT) has a modulatory effect on pain processing. Particularly strong evidence comes from …

Social touch—the affiliative skin-to-skin contact between individuals—can rapidly evoke
emotions of comfort, pleasure, or calm, and is essential for mental and physical well-being …

In an acute environment pain has potential protective benefits. However when pain
becomes chronic this protective effect is lost and the pain becomes an encumbrance …

Pain is a ubiquitously unpleasant feeling among humans as well as many animal species
often caused by actual and potential tissue damage. However, it is absolutely crucial for our …

Introduction: Protein and peptide-based drugs are preferred therapeutics due to their
specificity but are mainly administered by injection. Alternative routes for peptide delivery …

Abstract Oxytocin (OT) is a 9-amine neuropeptide that plays an essential role in mammalian
labor, lactation, maternal bonding, and social affiliation. OT has been reported to exert an …

The treatment of chronic pain arising from deep tissues is currently inadequate and there is
need for new pharmacological agents to provide analgesia. The endogenous paracrine …

Social support plays a vital role in physical and mental well‐being. The neuropeptide
hormone oxytocin (OXT) has been implicated in modulating pair‐bonding and affiliative …

Our empathetic abilities allow us to feel the pain of others. This phenomenon of vicarious
feeling arises because the neural circuitry of feeling pain and seeing pain in others is …