Cisplatin is a clinically advanced and highly effective anticancer drug used in the treatment
of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer …

Simple Summary Nephrotoxicity is the dose-limiting factor of cisplatin treatment.
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …

Cisplatin is a widely used chemotherapeutic agent used to treat solid tumours, such as
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …

Cells primarily rely on proteins to perform the majority of their physiological functions, and
the function of proteins is regulated by post-translational modifications (PTMs). The …

Cisplatin is a platinum-based chemotherapeutic that has long since been effective against a
variety of solid-cancers, substantially improving the five-year survival rates for cancer …

Aims To investigate the protective function of exosomes from adipose tissue-derived
mesenchymal stem cells (AMSCs) in sepsis-induced acute kidney injury (AKI) in mice and …

Cisplatin is a chemotherapeutic agent widely used in the treatment of various cancers.
However, cisplatin can induce nephrotoxicity and neurotoxicity, limiting its dosage and …

Cisplatin (CP) is a broad-spectrum antineoplastic agent, used to treat many different types of
malignancies due to its high efficacy and low cost. However, its use is largely limited by …

The discovery of STING-related innate immunity has recently provided a deep mechanistic
understanding of immunopathy. While the detrimental effects of STING during sepsis had …

Platinum-based anticancer drugs (PADs), mainly cisplatin, carboplatin, and oxaliplatin, are
widely used efficacious long-standing anticancer agents for treating several cancer types …