Chitosan-based nanomaterials: A state-of-the-art review

SK Shukla, AK Mishra, OA Arotiba… - International journal of …, 2013 - Elsevier
This manuscript briefly reviews the extensive research as well as new developments on
chitosan based nanomaterials for various applications. Chitosan is a biocompatible and …

Emerging micro-and nanotechnology based synthetic approaches for insulin delivery

R Mo, T Jiang, J Di, W Tai, Z Gu - Chemical society reviews, 2014 - pubs.rsc.org
Insulin is essential for type 1 and advanced type 2 diabetics to maintain blood glucose levels
and prolong lives. The traditional administration requires frequent subcutaneous insulin …

Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials

TAS Aguirre, D Teijeiro-Osorio, M Rosa… - Advanced drug delivery …, 2016 - Elsevier
The development of oral dosage forms that allows absorption of therapeutic peptides to the
systemic circulation is one of the greatest challenges for the pharmaceutical industry …

Chitosan nanoparticles: a promising system in novel drug delivery

K Nagpal, SK Singh, DN Mishra - Chemical and Pharmaceutical …, 2010 - jstage.jst.go.jp
The ability of nanoparticles to manipulate the molecules and their structures has
revolutionized the conventional drug delivery system. The chitosan nanoparticles, because …

Oral insulin delivery platforms: strategies to address the biological barriers

Y **ao, Z Tang, J Wang, C Liu, N Kong… - Angewandte Chemie …, 2020 - Wiley Online Library
Diabetes mellitus is a lifelong metabolic disease that requires frequent subcutaneous
injections of insulin. However, this method of administration can be associated with patient …

Potential of insulin nanoparticle formulations for oral delivery and diabetes treatment

CY Wong, H Al-Salami, CR Dass - Journal of controlled release, 2017 - Elsevier
Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …

Natural polymers: polysaccharides and their derivatives for biomedical applications

A Aravamudhan, DM Ramos, AA Nada… - Natural and synthetic …, 2014 - Elsevier
Several polymers of both natural and synthetic origin have been used for a variety of
biomedical applications including pharmaceutical preparations, drug targeting, imaging …

Recent advances in chitosan-based nanoparticles for oral delivery of macromolecules

MC Chen, FL Mi, ZX Liao, CW Hsiao, K Sonaje… - Advanced drug delivery …, 2013 - Elsevier
Chitosan (CS), a cationic polysaccharide, is widely regarded as a safe and efficient intestinal
absorption enhancer of therapeutic macromolecules, owing to its inherent mucoadhesive …

Chitosan nanoparticle encapsulation of antibacterial essential oils

A Negi, KK Kesari - Micromachines, 2022 - mdpi.com
Chitosan is the most suitable encapsulation polymer because of its natural abundance,
biodegradability, and surface functional groups in the form of free NH2 groups. The …

Nanoparticle delivery systems in the treatment of diabetes complications

EB Souto, SB Souto, JR Campos, P Severino… - Molecules, 2019 - mdpi.com
Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …