Small molecule tyrosine kinase inhibitors (TKIs) are widely used as anticancer drugs
approved by US FDA. However, the toxicities of TKIs to multiple organs have greatly limited …

Chemotherapy, radiotherapy, targeted therapy, and immunotherapy have brought hope to
cancer patients. With the prolongation of survival of cancer patients and increased clinical …

Pharmaceutical agents despite their efficacy to treat disease can cause additional unwanted
cardiovascular side effects. Cardiotoxicity is characterized by changes in either the function …

The prognosis of various cardiovascular diseases eventually leads to heart failure (HF). An
energy metabolism disorder of cardiomyocytes is important in explaining the molecular …

Background. Whether additional benefit can be achieved with the use of L‐carnitine (L‐C) in
patients with chronic heart failure (CHF) remains controversial. We therefore performed a …

Heart failure (HF) is a complex clinical syndrome that represents a major cause of morbidity
and mortality in Western countries. Several nutraceuticals have shown interesting clinical …

Carnitine can be considered a conditionally essential nutrient for its importance in human
physiology. This paper provides an updated picture of the main features of carnitine …

Exercise and competitive sports should be associated with a wide range of health benefits
with the potential to inspire a positive community health legacy. However, the reputation of …

Chemotherapy is a main treatment for cancer, and it benefits patients by controlling cancer
relapse and metastasis, thereby leading to an increase in the overall survival rate. However …

Cancer therapies have been evolving from conventional chemotherapeutics to targeted
agents. This has fulfilled the hope of greater efficacy but unfortunately not of greater safety …