N-Heterocyclic carbenes, despite being isolated and characterized three decades ago, still
capture scientists' interest as versatile, modular and strongly coordinating moieties. In the …

This Review compiles the evolution, mechanistic understanding, and more recent advances
in enantioselective Pd-catalyzed allylic substitution and decarboxylative and oxidative allylic …

Since its advent two decades ago, asymmetric organo/transition-metal combined catalysis
(AOMC), including cooperative catalysis and relay catalysis, has leveraged redistribution of …

Axial chirality widely exists in natural products, pharmaceutical compounds, and other
functional molecules; these axially chiral compounds also find wide utility as catalysts or …

Three-component carboacylation of simple alkenes with readily available reagents is
challenging. Transition metal-catalysed intermolecular carboacylation works for alkenes with …

N-Heterocyclic carbene (NHC) catalysis has emerged as a versatile tool in modern synthetic
chemistry. Further increasing the complexity, several processes have been introduced that …

Medium-sized heterocycles are widespread among a spectrum of structurally intriguing and
biologically significant natural products and synthetic pharmaceuticals. Metal-catalyzed high …

N-Heterocyclic carbene (NHC) organocatalysis to promote so-called umpolung reactions
has emerged as a powerful tool for modern organic synthesis. NHC-bound nucleophiles …

Spirooxindoles have emerged as promising architectures for engineering biologically active
compounds. The diastereodivergent construction of unique scaffolds of this type with full …

N‐Heterocyclic carbene (NHC) catalysis has emerged as a powerful stratagem in organic
synthesis to construct complex molecules primarily by polarity reversal (umpolung) …