Preparation of drug nanoparticles via wet media milling (nanomilling) is a very versatile drug
delivery platform and is suitable for oral, injectable, inhalable, and buccal applications. Wet …

The objective of this work is to present a review of computational tools and models for
pharmaceutical processes, specifically those for the continuous manufacture of solid dosage …

In this study, experimental data for wet-and dry-ground coal samples under wet and dry
grinding are characterized by commonly used distribution functions. First, both the RR and …

Abstract A coupled DEM+ SPH model can be used to predict the motion and breakage of
resolved coarser particles within a SAG mill. The fine product from coarse particle fracture …

This study investigated ultra-fine coal grinding performance of four low-to moderate-cost
grinding media in a laboratory stirred mill. Kinetic grinding tests showed that silica beads …

This study formulates a particle-scale breakage rate constant of the linear time-variant
population balance model (PBM) for batch dry-milling. The breakage rate constant …

Comminution studies have been carried out by grinding narrowly sized fractions of single
mineral feeds. Under these conditions, the mill environment remains self-similar and …

Over the years, circulating fluidized bed systems have been designed for chemical
conversion and energy recovery due to the ability of allowing continuous processing. While …

Non-linear population balance models (PBMs), which have been recently introduced due to
the limitations of the classical linear time-invariant (LTINV) model, account for multi-particle …

Abstract By means of Discrete-Element simulations with Bonded-Cell method for particle
breakage, we investigate the evolution of crushable granular materials in a 2D rotating drum …