Simple Summary An injury to the liver caused by a drug or its metabolites is referred to as
drug-induced liver injury (DILI). The clinical manifestations of DILI are varied, and it may …

Acute liver failure caused by drug overdose is a significant clinical problem in developed
countries. Acetaminophen (APAP), a widely used analgesic and antipyretic drug, but its …

Acetaminophen (APAP) overdose is the primary cause of drug-induced acute liver failure in
numerous Western countries. NLR family pyrin domain containing 3 (NLRP3) inflammasome …

Endotoxemia‐related acute liver injury has a poor prognosis and high mortality, and
macrophage polarization plays a central role in the pathological process. Pregnane X …

In many affluent nations, acetaminophen (APAP) overdose is the leading cause of drug-
induced acute liver failure. The process of APAP-induced liver injury (AILI) is intimately tied …

The tumor microenvironment is a highly heterogeneous circumstance composed of multiple
components, while tumor-associated macrophages (TAMs) are major innate immune cells …

Inferring cell type proportions from bulk transcriptome data is crucial in immunology and
oncology. Here, we introduce guided LDA deconvolution (GLDADec), a bulk deconvolution …

Background: Severe alcoholic hepatitis (AH) has a high short-term mortality rate. The MELD
assesses disease severity and mortality; however, it is not specific for AH. We screened …

Kimura's disease is a rare chronic inflammatory disorder characterized with subcutaneous
masses, lymphadenopathy, and peripheral eosinophilia. So far, the disease pathogenesis …

Background Acetaminophen (APAP)-induced hepatotoxicity is a major cause of acute liver
failure (ALF), during which autophagy is triggered as a cellular defense mechanism …