The evolving role of natural products in drug discovery
FE Koehn, GT Carter - Nature reviews Drug discovery, 2005 - nature.com
Natural products and their derivatives have historically been invaluable as a source of
therapeutic agents. However, in the past decade, research into natural products in the …
therapeutic agents. However, in the past decade, research into natural products in the …
Carbon-13 NMR spectroscopy of steroidal sapogenins and steroidal saponins
The 13 C NMR chemical shifts of 130 naturally occurring steroidal sapogenins and saponin
derivatives published up to 1983 are listed and a number of methods for signal assignment …
derivatives published up to 1983 are listed and a number of methods for signal assignment …
Two-dimensional infrared (2D IR) spectroscopy: theory and applications
I Noda - Applied Spectroscopy, 1990 - journals.sagepub.com
A novel concept in vibrational spectroscopy called two-dimensional infrared (2D IR)
spectroscopy is described. In 2D IR, a spectrum defined by two independent wavenumbers …
spectroscopy is described. In 2D IR, a spectrum defined by two independent wavenumbers …
[LIVRE][B] Experimental pulse NMR: a nuts and bolts approach
E Fukushima - 2018 - taylorfrancis.com
This book is about pulse nuclear magnetic resonance (NMR), with its techniques, the
information to be obtained, and practical advice on performing experiments. The emphasis …
information to be obtained, and practical advice on performing experiments. The emphasis …
A two-dimensional nuclear Overhauser experiment with pure absorption phase in four quadrants
DJ States, RA Haberkorn, DJ Ruben - Journal of Magnetic Resonance …, 1982 - Elsevier
A method is described for obtaining pure absorption phase spectra in four quadrants in a
two-dimensional nuclear magnetic resonance spin exchange experiment. It is shown that …
two-dimensional nuclear magnetic resonance spin exchange experiment. It is shown that …
Correlation of proton and nitrogen-15 chemical shifts by multiple quantum NMR
AD Bax, RH Griffey, BL Hawkins - Journal of Magnetic Resonance (1969), 1983 - Elsevier
Techniques for the correlation of 1 H and 15 N chemical shifts based on zero and double
quantum NMR are discussed. The indirect determination of nitrogen shifts from the proton …
quantum NMR are discussed. The indirect determination of nitrogen shifts from the proton …
Investigation of complex networks of spin-spin coupling by two-dimensional NMR
Proton-proton couplings in a sample of 9-hydroxytricyclodecan-2, 5-dione were studied by
the two-dimensional Fourier transform method proposed by Jeener. Various techniques …
the two-dimensional Fourier transform method proposed by Jeener. Various techniques …
Effect of the intramolecular charge separation distance on the solution properties of betaines and sulfobetaines
The solution properties of zwitterionic surfactants are shown to be strong functions of the
type of negatively charged center (carboxylate vs sulfonate) and the number of methylene …
type of negatively charged center (carboxylate vs sulfonate) and the number of methylene …
Sequential resonance assignments as a basis for determination of spatial protein structures by high resolution proton nuclear magnetic resonance
A general scheme is proposed for the determination of spatial protein structures by proton
nuclear magnetic resonance. The scheme relies on experimental observation by two …
nuclear magnetic resonance. The scheme relies on experimental observation by two …
[LIVRE][B] Quantum description of high-resolution NMR in liquids
M Goldman - 2001 - academic.oup.com
Available in paperback for the first time, this book describes the main methods of one-and
two-dimensional high-resolution NMR spectroscopy in liquids within the quantum …
two-dimensional high-resolution NMR spectroscopy in liquids within the quantum …