The evolving role of natural products in drug discovery

FE Koehn, GT Carter - Nature reviews Drug discovery, 2005 - nature.com
Natural products and their derivatives have historically been invaluable as a source of
therapeutic agents. However, in the past decade, research into natural products in the …

Carbon-13 NMR spectroscopy of steroidal sapogenins and steroidal saponins

PK Agrawal, DC Jain, RK Gupta, RS Thakur - Phytochemistry, 1985 - Elsevier
The 13 C NMR chemical shifts of 130 naturally occurring steroidal sapogenins and saponin
derivatives published up to 1983 are listed and a number of methods for signal assignment …

Two-dimensional infrared (2D IR) spectroscopy: theory and applications

I Noda - Applied Spectroscopy, 1990 - journals.sagepub.com
A novel concept in vibrational spectroscopy called two-dimensional infrared (2D IR)
spectroscopy is described. In 2D IR, a spectrum defined by two independent wavenumbers …

[LIVRE][B] Experimental pulse NMR: a nuts and bolts approach

E Fukushima - 2018 - taylorfrancis.com
This book is about pulse nuclear magnetic resonance (NMR), with its techniques, the
information to be obtained, and practical advice on performing experiments. The emphasis …

A two-dimensional nuclear Overhauser experiment with pure absorption phase in four quadrants

DJ States, RA Haberkorn, DJ Ruben - Journal of Magnetic Resonance …, 1982 - Elsevier
A method is described for obtaining pure absorption phase spectra in four quadrants in a
two-dimensional nuclear magnetic resonance spin exchange experiment. It is shown that …

Correlation of proton and nitrogen-15 chemical shifts by multiple quantum NMR

AD Bax, RH Griffey, BL Hawkins - Journal of Magnetic Resonance (1969), 1983 - Elsevier
Techniques for the correlation of 1 H and 15 N chemical shifts based on zero and double
quantum NMR are discussed. The indirect determination of nitrogen shifts from the proton …

Investigation of complex networks of spin-spin coupling by two-dimensional NMR

AD Bax, R Freeman - Journal of Magnetic Resonance (1969), 1981 - Elsevier
Proton-proton couplings in a sample of 9-hydroxytricyclodecan-2, 5-dione were studied by
the two-dimensional Fourier transform method proposed by Jeener. Various techniques …

Effect of the intramolecular charge separation distance on the solution properties of betaines and sulfobetaines

JG Weers, JF Rathman, FU Axe, CA Crichlow… - Langmuir, 1991 - ACS Publications
The solution properties of zwitterionic surfactants are shown to be strong functions of the
type of negatively charged center (carboxylate vs sulfonate) and the number of methylene …

Sequential resonance assignments as a basis for determination of spatial protein structures by high resolution proton nuclear magnetic resonance

K Wüthrich, G Wider, G Wagner, W Braun - Journal of molecular biology, 1982 - Elsevier
A general scheme is proposed for the determination of spatial protein structures by proton
nuclear magnetic resonance. The scheme relies on experimental observation by two …

[LIVRE][B] Quantum description of high-resolution NMR in liquids

M Goldman - 2001 - academic.oup.com
Available in paperback for the first time, this book describes the main methods of one-and
two-dimensional high-resolution NMR spectroscopy in liquids within the quantum …