On the importance of being flexible: dynamic brain networks and their potential functional significances

A Safron, V Klimaj, I Hipólito - Frontiers in Systems Neuroscience, 2022‏ - frontiersin.org
In this theoretical review, we begin by discussing brains and minds from a dynamical
systems perspective, and then go on to describe methods for characterizing the flexibility of …

[HTML][HTML] Fintech agents: Technologies and theories

A Pal, S Gopi, KM Lee - Electronics, 2023‏ - mdpi.com
Many financial technology (fintech) applications have incorporated interactive computer
agents to act as mediators between the user and the fintech system. This paper provides a …

Pattern breaking: a complex systems approach to psychedelic medicine

I Hipólito, J Mago, FE Rosas… - Neuroscience of …, 2023‏ - academic.oup.com
Recent research has demonstrated the potential of psychedelic therapy for mental health
care. However, the psychological experience underlying its therapeutic effects remains …

[PDF][PDF] Deep CANALs: A deep learning approach to refining the canalization theory of psychopathology

A Juliani, A Safron, R Kanai - Neuroscience of Consciousness, 2024‏ - academic.oup.com
Psychedelic therapy has seen a resurgence of interest in the last decade, with promising
clinical outcomes for the treatment of a variety of psychopathologies. In response to this …

On the varieties of conscious experiences: altered beliefs under psychedelics (ALBUS)

A Safron, A Juliani, N Reggente… - Neuroscience of …, 2025‏ - academic.oup.com
How is it that psychedelics so profoundly impact brain and mind? According to the model of
“Relaxed Beliefs Under Psychedelics”(REBUS), 5-HT2a agonism is thought to help relax …

[HTML][HTML] The radically embodied conscious cybernetic Bayesian brain: from free energy to free will and back again

A Safron - Entropy, 2021‏ - mdpi.com
Drawing from both enactivist and cognitivist perspectives on mind, I propose that explaining
teleological phenomena may require reappraising both “Cartesian theaters” and mental …

Consciousness, sapience and sentience—A metacybernetic view

M Yolles - Systems, 2022‏ - mdpi.com
Living systems are complex dynamic information processing energy consuming entities with
properties of consciousness, intelligence, sapience, and sentience. Sapience and sentience …

Enactivist big five theory

G Hovhannisyan, J Vervaeke - Phenomenology and the Cognitive …, 2022‏ - Springer
The distinguishing feature of enactivist cognitive science is arguably its commitment to non-
reductionism and its philosophical allegiance to first-person approaches, like …

Dream to explore: 5-HT2a as adaptive temperature parameter for sophisticated affective inference

A Safron, Z Sheikhbahaee - … machine learning and knowledge discovery in …, 2021‏ - Springer
Relative to other neuromodulators, serotonin (5-HT) has received far less attention in
machine learning and active inference. We will review prior work interpreting 5-HT1a …