Review of Geant4-DNA applications for micro and nanoscale simulations
Emerging radiotherapy treatments including targeted particle therapy, hadron therapy or
radiosensitisation of cells by high-Z nanoparticles demand the theoretical determination of …
radiosensitisation of cells by high-Z nanoparticles demand the theoretical determination of …
AOP report: Development of an adverse outcome pathway for deposition of energy leading to cataracts
E Carrothers, M Appleby, V Lai… - Environmental and …, 2024 - Wiley Online Library
Cataracts are one of the leading causes of blindness, with an estimated 95 million people
affected worldwide. A hallmark of cataract development is lens opacification, typically …
affected worldwide. A hallmark of cataract development is lens opacification, typically …
Monte Carlo investigation of the increased radiation deposition due to gold nanoparticles using kilovoltage and megavoltage photons in a 3D randomized cell model
Purpose: Investigation of increased radiation dose deposition due to gold nanoparticles
(GNPs) using a 3D computational cell model during x‐ray radiotherapy. Methods: Two GNP …
(GNPs) using a 3D computational cell model during x‐ray radiotherapy. Methods: Two GNP …
Nanoscale radiation transport and clinical beam modeling for gold nanoparticle dose enhanced radiotherapy (GNPT) using X-rays
P Zygmanski, E Sajo - The British journal of radiology, 2016 - academic.oup.com
We review radiation transport and clinical beam modelling for gold nanoparticle dose-
enhanced radiotherapy using X-rays. We focus on the nanoscale radiation transport and its …
enhanced radiotherapy using X-rays. We focus on the nanoscale radiation transport and its …
Future development of biologically relevant dosimetry
Proton and ion beams are radiotherapy modalities of increasing importance and interest.
Because of the different biological dose response of these radiations as compared with high …
Because of the different biological dose response of these radiations as compared with high …
Geometrical structures for radiation biology research as implemented in the TOPAS-nBio toolkit
Computational simulations, such as Monte Carlo track structure simulations, offer a powerful
tool for quantitatively investigating radiation interactions within cells. The modelling of the …
tool for quantitatively investigating radiation interactions within cells. The modelling of the …
[HTML][HTML] Intercomparison of Monte Carlo calculated dose enhancement ratios for gold nanoparticles irradiated by X-rays: Assessing the uncertainty and correct …
Abstract Results of a Monte Carlo code intercomparison exercise for simulations of the dose
enhancement from a gold nanoparticle (GNP) irradiated by X-rays have been recently …
enhancement from a gold nanoparticle (GNP) irradiated by X-rays have been recently …
Computed tomography imaging-guided radiotherapy by targeting upconversion nanocubes with significant imaging and radiosensitization enhancements
H **ng, X Zheng, Q Ren, W Bu, W Ge, Q **ao… - Scientific reports, 2013 - nature.com
The clinical potentials of radiotherapy could not be achieved completely because of the
inaccurate positioning and inherent radioresistance of tumours. In this study, a novel active …
inaccurate positioning and inherent radioresistance of tumours. In this study, a novel active …
AOP report: Development of an adverse outcome pathway for deposition of energy leading to learning and memory impairment
A Sleiman, KB Miller, D Flores, J Kuan… - Environmental and …, 2024 - Wiley Online Library
Understanding radiation‐induced non‐cancer effects on the central nervous system (CNS)
is essential for the risk assessment of medical (eg, radiotherapy) and occupational (eg …
is essential for the risk assessment of medical (eg, radiotherapy) and occupational (eg …
AOP Report: Development of an adverse outcome pathway for deposition of energy leading to bone loss
S Sandhu, M Keyworth, S Karimi‐Jashni… - Environmental and …, 2024 - Wiley Online Library
Bone loss, commonly seen in osteoporosis, is a condition that entails a progressive decline
of bone mineral density and microarchitecture, often seen in post‐menopausal women …
of bone mineral density and microarchitecture, often seen in post‐menopausal women …