Cell fate determination, a vital process in early development and adulthood, has been the
focal point of intensive investigation over the past decades. Its importance lies in its critical …

Emerging human pluripotent stem cell (hPSC)-based embryo models are useful for studying
human embryogenesis. Particularly, there are hPSC-based somitogenesis models using …

Animal morphogenesis, the development of an organism's body form, is commonly
perceived as a directed and almost deterministic process. However, noise and stochastic …

Surface morphological patterns are widely observed in natural systems, which are closely
correlated to vital biological functions and inspire surface morphology designs in soft matter …

In the intricately defined spatial microenvironment, a single fertilized egg remarkably
develops into a conserved and well-organized multicellular organism. This observation …

During developmental processes such as embryogenesis, how a group of cells fold into
specific structures, is a central question in biology. However, it remains a major challenge to …

Couplings between biochemical and mechanical processes have a profound impact on
embryonic development. However, in-vitro studies capable of quantifying these interactions …

Current 4D materials typically rely on external stimuli such as heat or light to accomplish
changes in shape, limiting the biocompatibility of these materials. Here, a composite bioink …

We study two separate systems each of which emphasizes the geometrical and topological
aspects of soft condensed matter systems. The geometry side of condensed matter is …

抄録 Tissue patterning during organ development consists of intricate morphogenetic
processes, driven by the interplay of physical and genetic cues among constituent cells …