The let-7 miRNA was one of the first miRNAs discovered in the nematode, Caenorhabditis
elegans, and its biological functions show a high level of evolutionary conservation from the …

In normal cells multiple microRNAs (miRNAs) converge to maintain a proper balance of
various processes, including proliferation, differentiation and cell death. miRNA …

Abnormal regulation and expression of microRNAs (miRNAs) has been documented in
various diseases including cancer. The miRNA let-7 (MIRLET7) family controls …

Two major functions of the mammalian ovary are the production of germ cells (oocytes),
which allow continuation of the species, and the generation of bioactive molecules, primarily …

Background Cell-derived microvesicles (MVs) have been described as a new mechanism of
cell-to-cell communication. MVs after internalization within target cells may deliver genetic …

Abstract Using RNA sequencing (RNA-Seq), we compared the expression patterns of
circular RNAs in proliferating (early-passage) and senescent (late-passage) human diploid …

MicroRNAs (miRNAs or miRs) are small noncoding RNAs capable of regulating gene
expression at the translational level. Current evidence suggests that a significant portion of …

Specific and sensitive non‐invasive biomarkers for the detection of human epithelial
malignancies are urgently required to reduce the worldwide morbidity and mortality caused …

An analytical platform for the selective miRNA-21-guided imaging of breast cancer cells and
miRNA-221-guided imaging of ovarian cancer cells and the selective photodynamic therapy …

Recent evidence supports a role for microRNAs (miRNAs) in regulating the life span of
model organisms. However, little is known about how these small RNAs contribute to human …