Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Evolutionary Emergence of Drug Resistance in Candida Opportunistic Pathogens

E Ksiezopolska, T Gabaldón - Genes, 2018 - mdpi.com
Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …

[BOOK][B] Introduction to fungi

J Webster, R Weber - 2007 - books.google.com
This new edition of the universally acclaimed and widely-used textbook on fungal biology
has been completely re-written, drawing directly on the authors' research and teaching …

The diploid genome sequence of Candida albicans

T Jones, NA Federspiel, H Chibana… - Proceedings of the …, 2004 - National Acad Sciences
We present the diploid genome sequence of the fungal pathogen Candida albicans.
Because C. albicans has no known haploid or homozygous form, sequencing was …

Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi

LE Cowen, S Lindquist - Science, 2005 - science.org
Hsp90 is a molecular chaperone for many signal transducers and may influence evolution
by releasing previously silent genetic variation in response to environmental change. In …

Scent of a killer: microbial volatilome and its role in the biological control of plant pathogens

B Tilocca, A Cao, Q Migheli - Frontiers in Microbiology, 2020 - frontiersin.org
The use of synthetic fungicides represents the most common strategy to control plant
pathogens. Excessive and/or long-term distribution of chemicals is responsible for increased …

The evolution of drug resistance in clinical isolates of Candida albicans

CB Ford, JM Funt, D Abbey, L Issi, C Guiducci… - elife, 2015 - elifesciences.org
Candida albicans is both a member of the healthy human microbiome and a major pathogen
in immunocompromised individuals. Infections are typically treated with azole inhibitors of …

Is the efficacy of biological control against plant diseases likely to be more durable than that of chemical pesticides?

M Bardin, S Ajouz, M Comby, M Lopez-Ferber… - Frontiers in Plant …, 2015 - frontiersin.org
The durability of a control method for plant protection is defined as the persistence of its
efficacy in space and time. It depends on (i) the selection pressure exerted by it on …

Members of the Fusarium solani Species Complex That Cause Infections in Both Humans and Plants Are Common in the Environment

N Zhang, K O'Donnell, DA Sutton… - Journal of Clinical …, 2006 - Am Soc Microbiol
Members of the Fusarium solani species complex (FSSC) are increasingly implicated as the
causative agents of human mycoses, particularly in the expanding immunocompromised …

The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatus

MG Fraczek, M Bromley, A Buied… - Journal of …, 2013 - academic.oup.com
Objectives Recent increases in triazole resistance in Aspergillus fumigatus have been
attributed primarily to target site (cyp51A) mutations. A recent survey of resistant isolates in …