The intrinsic electrical properties and the synaptic input-output relationships of neurons are
governed by the action of voltage-dependent ion channels. The localization of specific …

The intrinsic electrical properties of neurons are shaped in large part by the action of voltage-
gated ion channels. Molecular cloning studies have revealed a large family of ion channel …

Voltage gated calcium channels (Ca2+ channels) are key mediators of depolarization
induced calcium influx into excitable cells, and thereby play pivotal roles in a wide array of …

Homeostatic scaling is a non-Hebbian form of neural plasticity that maintains neuronal
excitability and informational content of synaptic arrays in the face of changes of network …

The role of Gβγ subunits in cellular signaling has become well established in the past 20
years. Not only do they regulate effectors once thought to be the sole targets of Gα subunits …

Serological testing for anti-neural autoantibodies is important in patients presenting with
idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine …

Almost 25 years after the first report that glutamate can activate receptors coupled to
heterotrimeric G-proteins, tremendous progress has been made in the field of metabotropic …

G protein-coupled receptors (GPCR) interact not only with heterotrimeric G proteins but also
with accessory proteins called GPCR interacting proteins (GIP). These proteins have …

Recent developments have implicated cannabinoid CB 1 receptors as a novel target for a
new class of therapeutic agents used to treat drug addiction. CB 1 receptors are expressed …

P/Q-type voltage-dependent calcium channels play key roles in transmitter release,
integration of dendritic signals, generation of dendritic spikes, and gene expression. High …