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Progression in translational research on spinal cord injury based on microenvironment imbalance
B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …
and imposes a considerable burden on patients, families, and society. Repair of the injured …
Recent progress and challenges in the treatment of spinal cord injury
T Tian, S Zhang, M Yang - Protein & cell, 2023 - academic.oup.com
Spinal cord injury (SCI) disrupts the structural and functional connectivity between the higher
center and the spinal cord, resulting in severe motor, sensory, and autonomic dysfunction …
center and the spinal cord, resulting in severe motor, sensory, and autonomic dysfunction …
[HTML][HTML] Walking naturally after spinal cord injury using a brain–spine interface
H Lorach, A Galvez, V Spagnolo, F Martel, S Karakas… - Nature, 2023 - nature.com
A spinal cord injury interrupts the communication between the brain and the region of the
spinal cord that produces walking, leading to paralysis 1, 2. Here, we restored this …
spinal cord that produces walking, leading to paralysis 1, 2. Here, we restored this …
Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis
Epidural electrical stimulation (EES) targeting the dorsal roots of lumbosacral segments
restores walking in people with spinal cord injury (SCI). However, EES is delivered with …
restores walking in people with spinal cord injury (SCI). However, EES is delivered with …
Epidural stimulation of the cervical spinal cord for post-stroke upper-limb paresis
Cerebral strokes can disrupt descending commands from motor cortical areas to the spinal
cord, which can result in permanent motor deficits of the arm and hand. However, below the …
cord, which can result in permanent motor deficits of the arm and hand. However, below the …
Multifunctional conductive and electrogenic hydrogel repaired spinal cord injury via immunoregulation and enhancement of neuronal differentiation
M Liu, W Zhang, S Han, D Zhang, X Zhou… - Advanced …, 2024 - Wiley Online Library
Spinal cord injury (SCI) is a refractory neurological disorder. Due to the complex
pathological processes, especially the secondary inflammatory cascade and the lack of …
pathological processes, especially the secondary inflammatory cascade and the lack of …
Electrical stimulation for the treatment of spinal cord injuries: A review of the cellular and molecular mechanisms that drive functional improvements
Spinal cord injury (SCI) is a devastating condition that causes severe loss of motor, sensory
and autonomic functions. Additionally, many individuals experience chronic neuropathic …
and autonomic functions. Additionally, many individuals experience chronic neuropathic …
Therapeutic acute intermittent hypoxia: A translational roadmap for spinal cord injury and neuromuscular disease
We review progress towards greater mechanistic understanding and clinical translation of a
strategy to improve respiratory and non-respiratory motor function in people with …
strategy to improve respiratory and non-respiratory motor function in people with …
Single-cell analysis reveals region-heterogeneous responses in rhesus monkey spinal cord with complete injury
Y Fan, X Wu, S Han, Q Zhang, Z Sun, B Chen… - Nature …, 2023 - nature.com
Spinal cord injury (SCI) leads to severe sensory and motor dysfunction below the lesion.
However, the cellular dynamic responses and heterogeneity across different regions below …
However, the cellular dynamic responses and heterogeneity across different regions below …
Sensory restoration by epidural stimulation of the lateral spinal cord in upper-limb amputees
Restoring somatosensory feedback to people with limb amputations is crucial to improve
prosthetic control. Multiple studies have demonstrated that peripheral nerve stimulation and …
prosthetic control. Multiple studies have demonstrated that peripheral nerve stimulation and …