Biomarker-driven molecular imaging probes in radiotherapy

H Li, Q Gong, K Luo - Theranostics, 2024 - pmc.ncbi.nlm.nih.gov
Background: Biomarker-driven molecular imaging has emerged as an integral part of cancer
precision radiotherapy. The use of molecular imaging probes, including nanoprobes, have …

Transition-metal-based nanozymes: synthesis, mechanisms of therapeutic action, and applications in cancer treatment

Q Fu, C Wei, M Wang - ACS nano, 2024 - ACS Publications
Cancer, as one of the leading causes of death worldwide, drives the advancement of cutting-
edge technologies for cancer treatment. Transition-metal-based nanozymes emerge as …

Augmenting cancer therapy with a supramolecular immunogenic cell death inducer: A lysosome-targeted NIR-light-activated ruthenium (II) metallacycle

L Tu, C Li, Q Ding, A Sharma, M Li, J Li… - Journal of the …, 2024 - ACS Publications
Though immunogenic cell death (ICD) has garnered significant attention in the realm of
anticancer therapies, effectively stimulating strong immune responses with minimal side …

Nanoparticle‐mediated radiotherapy remodels the tumor microenvironment to enhance antitumor efficacy

W Zhen, RR Weichselbaum, W Lin - Advanced Materials, 2023 - Wiley Online Library
Radiotherapy (RT) uses ionizing radiation to eradicate localized tumors and, in rare cases,
control tumors outside of the irradiated fields via stimulating an antitumor immune response …

Octadecyl Gallate and Lipid‐Modified MnSe2 Nanoparticles Enhance Radiosensitivity in Esophageal Squamous Cell Carcinoma and Promote Radioprotection in …

X Li, H Liu, W Gao, Q Yang, X Li, X Zhou… - Advanced …, 2024 - Wiley Online Library
Radiotherapy, a widely used therapeutic strategy for esophageal squamous cell carcinoma
(ESCC), is always limited by radioresistance of tumor tissues and side‐effects on normal …

Immunological nanomaterials to combat cancer metastasis

Y Pan, J Cheng, Y Zhu, J Zhang, W Fan… - Chemical Society …, 2024 - pubs.rsc.org
Metastasis causes greater than 90% of cancer-associated deaths, presenting huge
challenges for detection and efficient treatment of cancer due to its high heterogeneity and …

Advancing nanotechnology for neoantigen-based cancer theranostics

J Zou, Y Zhang, Y Pan, Z Mao, X Chen - Chemical Society Reviews, 2024 - pubs.rsc.org
Neoantigens play a pivotal role in the field of tumour therapy, encompassing the stimulation
of anti-tumour immune response and the enhancement of tumour targeting capability …

A multifunctional covalent organic framework nanozyme for promoting ferroptotic radiotherapy against esophageal cancer

LL Zhou, Q Guan, W Zhou, JL Kan, K Teng, M Hu… - ACS …, 2023 - ACS Publications
Radiotherapy is inevitably accompanied by some degree of radiation resistance, which
leads to local recurrence and even therapeutic failure. To overcome this limitation, herein …

Engineered living materials for advanced diseases therapy

X Dong, W Wu, P Pan, XZ Zhang - Advanced Materials, 2023 - Wiley Online Library
Natural living materials serving as biotherapeutics exhibit great potential for treating various
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …

A NIR‐Light‐Activated and Lysosomal‐Targeted Pt (II) Metallacycle for Highly Potent Evoking of Immunogenic Cell Death that Potentiates Cancer Immunotherapy of …

C Li, L Tu, Y Xu, M Li, J Du, PJ Stang… - Angewandte …, 2024 - Wiley Online Library
Though platinum (Pt)‐based complexes have been recently exploited as immunogenic cell
death (ICD) inducers for activating immunotherapy, the effective activation of sufficient …