Three decades of ultrasound contrast agents: a review of the past, present and future improvements

P Frinking, T Segers, Y Luan, F Tranquart - Ultrasound in medicine & …, 2020 - Elsevier
Initial reports from the 1960s describing the observations of ultrasound contrast
enhancement by tiny gaseous bubbles during echocardiographic examinations prompted …

[HTML][HTML] Ultrasound contrast agent modeling: a review

M Versluis, E Stride, G Lajoinie, B Dollet… - Ultrasound in medicine & …, 2020 - Elsevier
Ultrasound is extensively used in medical imaging, being safe and inexpensive and
operating in real time. Its scope of applications has been widely broadened by the use of …

The role of ultrasound-driven microbubble dynamics in drug delivery: From microbubble fundamentals to clinical translation

S Roovers, T Segers, G Lajoinie, J Deprez, M Versluis… - Langmuir, 2019 - ACS Publications
In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …

Microbubble agents: new directions

E Stride, T Segers, G Lajoinie, S Cherkaoui… - Ultrasound in medicine …, 2020 - Elsevier
Microbubble ultrasound contrast agents have now been in use for several decades and their
safety and efficacy in a wide range of diagnostic applications have been well established …

Microbubbles for human diagnosis and therapy

L Fournier, T de La Taille, C Chauvierre - Biomaterials, 2023 - Elsevier
Microbubbles (MBs) were observed for the first time in vivo as a curious consequence of
quick saline injection during ultrasound (US) imaging of the aortic root, more than 50 years …

Therapeutic oxygen delivery by perfluorocarbon-based colloids

MP Krafft, JG Riess - Advances in colloid and interface science, 2021 - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Probing the pressure dependence of sound speed and attenuation in bubbly media: Experimental observations, a theoretical model and numerical calculations

AJ Sojahrood, Q Li, H Haghi, R Karshafian… - Ultrasonics …, 2023 - Elsevier
The problem of attenuation and sound speed of bubbly media has remained partially
unsolved. Comprehensive data regarding pressure-dependent changes of the attenuation …

Highly focused high-frequency travelling surface acoustic waves (SAW) for rapid single-particle sorting

DJ Collins, A Neild, Y Ai - Lab on a Chip, 2016 - pubs.rsc.org
High-speed sorting is an essential process in a number of clinical and research applications,
where single cells, droplets and particles are segregated based on their properties in a …

Microbubble formulations: synthesis, stability, modeling and biomedical applications

A Upadhyay, SV Dalvi - Ultrasound in medicine & biology, 2019 - Elsevier
Microbubbles are increasingly being used in biomedical applications such as ultrasonic
imaging and targeted drug delivery. Microbubbles typically range from 0.1 to 10 µm in size …

[HTML][HTML] Dependence of sonoporation efficiency on microbubble size: An in vitro monodisperse microbubble study

B van Elburg, J Deprez, M van den Broek… - Journal of Controlled …, 2023 - Elsevier
Sonoporation is the process where intracellular drug delivery is facilitated by ultrasound-
driven microbubble oscillations. Several mechanisms have been proposed to relate …