HIV-1 and human genetic variation
Over the past four decades, research on the natural history of HIV infection has described
how HIV wreaks havoc on human immunity and causes AIDS. HIV host genomic research …
how HIV wreaks havoc on human immunity and causes AIDS. HIV host genomic research …
The impact of host genetic variation on infection with HIV-1
PJ McLaren, M Carrington - Nature immunology, 2015 - nature.com
The outcome after infection with the human immunodeficiency virus type 1 (HIV-1) is a
complex phenotype determined by interactions among the pathogen, the human host and …
complex phenotype determined by interactions among the pathogen, the human host and …
Immunogenetics of HIV disease
MP Martin, M Carrington - Immunological reviews, 2013 - Wiley Online Library
Host genetic factors are a major contributing factor to the inter‐individual variation observed
in response to human immunodeficiency virus (HIV) infection and are linked to resistance to …
in response to human immunodeficiency virus (HIV) infection and are linked to resistance to …
Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls
Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected
individuals, identifying common genetic influences on viral control and disease course …
individuals, identifying common genetic influences on viral control and disease course …
G protein-coupled receptor (GPCR) pharmacogenomics
The field of pharmacogenetics, the investigation of the influence of one or more sequence
variants on drug response phenotypes, is a special case of pharmacogenomics, a discipline …
variants on drug response phenotypes, is a special case of pharmacogenomics, a discipline …
Interleukins and cytokine biomarkers in uveitis
Interleukins and cytokines are involved in the pathogenesis of uveitis of heterogeneous
origin. Understanding the basics of the ocular immune privilege is a fulcrum to discern their …
origin. Understanding the basics of the ocular immune privilege is a fulcrum to discern their …
[HTML][HTML] Prevention of SHIV transmission by topical IFN-β treatment
Understanding vaginal and rectal HIV transmission and protective cellular and molecular
mechanisms is critical for designing new prevention strategies, including those required for …
mechanisms is critical for designing new prevention strategies, including those required for …
Pharmacogenetics of the G protein-coupled receptors
Pharmacogenetics investigates the influence of genetic variants on physiological
phenotypes related to drug response and disease, while pharmacogenomics takes a …
phenotypes related to drug response and disease, while pharmacogenomics takes a …
Cytokines and biologics in non-infectious autoimmune uveitis: bench to bedside
R Agrawal, J Iyer, J Connolly, D Iwata… - Indian Journal of …, 2014 - journals.lww.com
Intraocular inflammatory eye disease is one of the important causes of ocular morbidity.
Even though the prevalence of uveitis is less common in relation to diabetic retinopathy …
Even though the prevalence of uveitis is less common in relation to diabetic retinopathy …
Immunogenetics: Genome-Wide Association of Non-Progressive HIV and Viral Load Control: HLA Genes and Beyond
S Limou, JF Zagury - Frontiers in immunology, 2013 - frontiersin.org
Very early after the identification of the human immunodeficiency virus (HIV), host genetics
factors were anticipated to play a role in viral control and disease progression. As early as …
factors were anticipated to play a role in viral control and disease progression. As early as …