Short peptide nanofiber biomaterials ameliorate local hemostatic capacity of surgical materials and intraoperative hemostatic applications in clinics

Z Yang, L Chen, J Liu, H Zhuang, W Lin… - Advanced …, 2023 - Wiley Online Library
Short designer self‐assembling peptide (dSAP) biomaterials are a new addition to the
hemostat group. It may provide a diverse and robust toolbox for surgeons to integrate wound …

Modeling the neuroimmune system in Alzheimer's and Parkinson's diseases

W Balestri, R Sharma, VA da Silva, BC Bobotis… - Journal of …, 2024 - Springer
Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
caused by the interaction of genetic, environmental, and familial factors. These diseases …

Functional bioengineered models of the central nervous system

N Rouleau, NJ Murugan, DL Kaplan - Nature Reviews Bioengineering, 2023 - nature.com
The functional complexity of the central nervous system (CNS) is unparalleled in living
organisms. Its nested cells, circuits and networks encode memories, move bodies and …

[HTML][HTML] Unraveling brain diseases: the promise of brain-on-a-chip models

L Cerutti, M Brofiga - Journal of Neuroscience Methods, 2024 - Elsevier
Brain disorders, encompassing a wide spectrum of neurological and psychiatric conditions,
present a formidable challenge in modern medicine. Despite decades of research, the …

The impact of mechanical cues on the metabolomic and transcriptomic profiles of human dermal fibroblasts cultured in ultrashort self-assembling peptide 3D scaffolds

S Abdelrahman, R Ge, HH Susapto, Y Liu, F Samkari… - ACS …, 2023 - ACS Publications
Cells' interactions with their microenvironment influence their morphological features and
regulate crucial cellular functions including proliferation, differentiation, metabolism, and …

Drug Evaluation of Parkinson's disease patient-derived midbrain organoids using mesoporous Au nanodot-patterned 3D concave electrode

J An, M Shin, G Beak, J Yoon, S Kim, HY Cho… - ACS …, 2024 - ACS Publications
Brain organoids are being recognized as valuable tools for drug evaluation in
neurodegenerative diseases due to their similarity to the human brain's structure and …

3D printing of bone and cartilage with polymer materials

D Fan, Y Liu, Y Wang, Q Wang, H Guo, Y Cai… - Frontiers in …, 2022 - frontiersin.org
Damage and degeneration to bone and articular cartilage are the leading causes of
musculoskeletal disability. Commonly used clinical and surgical methods include …

Three-dimensional neuroimmune co-culture system for modeling Parkinson's disease microenvironments in vitro

L Rueda-Gensini, JA Serna, D Rubio, JC Orozco… - …, 2023 - iopscience.iop.org
Parkinson's disease (PD) is a complex and multifaceted neurodegenerative disorder that
results from multiple environmental factors and multicellular interactions. Although several …

Parkinson's disease: current status, diagnosis, and treatment using nanomedicines

I Hasan, S Roy, B Guo, C Chang - Advanced Therapeutics, 2023 - Wiley Online Library
Parkinson's disease (PD) is a chronic, and highly neurodegenerative disorder with complex
pathological processes. The features for neuropathological identification of PD include α …

[HTML][HTML] Recent advances in 3D bioprinted neural models: A systematic review on the applications to drug discovery

A Orr, F Kalantarnia, S Nazir, B Bolandi… - Advanced Drug Delivery …, 2025 - Elsevier
The design of neural tissue models with architectural and biochemical relevance to native
tissues opens the way for the fundamental study and development of therapies for many …