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Neurodevelopmental disorders—high-resolution rethinking of disease modeling
K Khodosevich, CM Sellgren - Molecular Psychiatry, 2023 - nature.com
Neurodevelopmental disorders arise due to various risk factors that can perturb different
stages of brain development, and a combinatorial impact of these risk factors programs the …
stages of brain development, and a combinatorial impact of these risk factors programs the …
Inhibition of glycogen synthase kinase 3 by lithium, a mechanism in search of specificity
D Chatterjee, JM Beaulieu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Inhibition of Glycogen synthase kinase 3 (GSK3) is a popular explanation for the effects of
lithium ions on mood regulation in bipolar disorder and other mental illnesses, including …
lithium ions on mood regulation in bipolar disorder and other mental illnesses, including …
Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development
Fragile X messenger ribonucleoprotein 1 protein (FMRP) deficiency leads to fragile X
syndrome (FXS), an autism spectrum disorder. The role of FMRP in prenatal human brain …
syndrome (FXS), an autism spectrum disorder. The role of FMRP in prenatal human brain …
Metasurface‐enhanced mid‐infrared spectrochemical imaging of tissues
Label‐free and nondestructive mid‐infrared vibrational hyperspectral imaging is an
essential tissue analysis tool, providing spatially resolved biochemical information critical to …
essential tissue analysis tool, providing spatially resolved biochemical information critical to …
Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway
Fragile X messenger ribonucleoprotein 1 protein (FMRP) binds many mRNA targets in the
brain. The contribution of these targets to fragile X syndrome (FXS) and related autism …
brain. The contribution of these targets to fragile X syndrome (FXS) and related autism …
Gamma oscillation plasticity is mediated via parvalbumin interneurons
Understanding the plasticity of neuronal networks is an emerging field of (patho-)
physiological research, yet the underlying cellular mechanisms remain poorly understood …
physiological research, yet the underlying cellular mechanisms remain poorly understood …
circ2CBA: prediction of circRNA-RBP binding sites combining deep learning and attention mechanism
Abstract Circular RNAs (circRNAs) are RNAs with closed circular structure involved in many
biological processes by key interactions with RNA binding proteins (RBPs). Existing …
biological processes by key interactions with RNA binding proteins (RBPs). Existing …
Parvalbumin interneuron cell-to-network plasticity: Mechanisms and therapeutic avenues
MD Hadler, H Alle, JRP Geiger - Trends in Pharmacological Sciences, 2024 - cell.com
Alzheimer's disease (AD) and schizophrenia (SCZ) represent two major neuropathological
conditions with a high disease burden. Despite their distinct etiologies, patients suffering …
conditions with a high disease burden. Despite their distinct etiologies, patients suffering …
Genetic influences on the develo** young brain and risk for neuropsychiatric disorders
Imaging genetics provides an opportunity to discern associations between genetic variants
and brain imaging phenotypes. Historically, the field has focused on adults and adolescents; …
and brain imaging phenotypes. Historically, the field has focused on adults and adolescents; …
Interneuron odyssey: molecular mechanisms of tangential migration
I Toudji, A Toumi, É Chamberland… - Frontiers in Neural …, 2023 - frontiersin.org
Cortical GABAergic interneurons are critical components of neural networks. They provide
local and long-range inhibition and help coordinate network activities involved in various …
local and long-range inhibition and help coordinate network activities involved in various …