COVID-19 vaccines: The status and perspectives in delivery points of view

JY Chung, MN Thone, YJ Kwon - Advanced drug delivery reviews, 2021 - Elsevier
Due to the high prevalence and long incubation periods often without symptoms, the severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …

Efficacy of chloroquine or hydroxychloroquine in COVID-19 patients: a systematic review and meta-analysis

Z Kashour, M Riaz, MA Garbati… - Journal of …, 2021 - academic.oup.com
Objectives Clinical studies of chloroquine (CQ) and hydroxychloroquine (HCQ) in COVID-19
disease reported conflicting results. We sought to systematically evaluate the effect of CQ …

SARS-CoV-2 and the nervous system: from clinical features to molecular mechanisms

M Pennisi, G Lanza, L Falzone, F Fisicaro… - International journal of …, 2020 - mdpi.com
Increasing evidence suggests that Severe Acute Respiratory Syndrome-coronavirus-2
(SARS-CoV-2) can also invade the central nervous system (CNS). However, findings …

Microstructure, pathophysiology, and potential therapeutics of COVID‐19: a comprehensive review

SP Singh, M Pritam, B Pandey… - Journal of medical …, 2021 - Wiley Online Library
There have been over seven million cases and almost 413 372 deaths globally due to the
novel coronavirus (2019‐nCoV) associated disease COVID‐19, as of 11 June 2020 …

Hydroxychloroquine in COVID-19: potential mechanism of action against SARS-CoV-2

S Satarker, T Ahuja, M Banerjee, VB E, S Dogra… - Current pharmacology …, 2020 - Springer
Abstract Purpose of Review The rapid spread of virus, severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has turned out to be a global emergency. Symptoms of this …

High prevalence of antibiotic resistance in commensal Escherichia coli from healthy human sources in community settings

E Nji, J Kazibwe, T Hambridge, CA Joko, AA Larbi… - Scientific reports, 2021 - nature.com
Antibiotic resistance is a global health crisis that requires urgent action to stop its spread. To
counteract the spread of antibiotic resistance, we must improve our understanding of the …

Healthcare workers & SARS-CoV-2 infection in India: A case-control investigation in the time of COVID-19

P Chatterjee, T Anand, KJ Singh… - Indian Journal of …, 2020 - journals.lww.com
Methods: A case-control design was adopted and participants were randomly drawn from
the countrywide COVID-19 testing data portal maintained by the ICMR. The test results and …

Gut microbiota dysbiosis–immune hyperresponse–inflammation triad in coronavirus disease 2019 (COVID-19): Impact of pharmacological and nutraceutical …

C Ferreira, SD Viana, F Reis - Microorganisms, 2020 - mdpi.com
Coronavirus Disease 2019 (COVID-19) is a pandemic infection caused by a novel
coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2

H Zhao, KKW To, H Lam, X Zhou, JFW Chan… - Nature …, 2021 - nature.com
Up to date, effective antivirals have not been widely available for treating COVID-19. In this
study, we identify a dual-functional cross-linking peptide 8P9R which can inhibit the two …

Molecular docking identification for the efficacy of some zinc complexes with chloroquine and hydroxychloroquine against main protease of COVID-19

RK Hussein, HM Elkhair - Journal of Molecular Structure, 2021 - Elsevier
Vast amount of research has been recently conducted to discover drugs for efficacious
treatment of corona virus disease 2019 (COVID-19). The ambiguity about using …