Leukemia is a malignancy of the hematopoietic system, and as its pathogenesis has
become better understood, three generations of tyrosine kinase inhibitors (TKIs) have been …

In the last decades, many nanovectors were developed for different diagnostic or therapeutic
purposes. However, most nanosystems have been designed using a “bottom-up” approach …

Biomimetic nanoparticles aim to effectively emulate the behavior of either cells or exosomes.
Leukocyte-based biomimetic nanoparticles, for instance, incorporate cell membrane …

Traumatic brain injury (TBI) triggers both central and peripheral inflammatory responses.
Existing pharmacological drugs are unable to effectively and quickly target the brain …

Nanovesicles (NVs) are emerging as innovative, theranostic tools for cargo delivery.
Recently, surface engineering of NVs with membrane proteins from specific cell types has …

Nanotechnology is an important application in modern cancer therapy. In comparison with
conventional drug formulations, nanoparticles ensure better penetration into the tumor mass …

Key Points• Why do we need biomimicry? Which challenges does it aim to overcome?•
Systemic delivery of free drugs has limitations. These limitations include rapid systemic …

Cancer therapy faces many challenges, such as inadequate drug loading, low solubility,
leakage before reaching the target cells and killing healthy cells. Furthermore, severe side …

BACKGROUND: Mitochondrial dysfunction is a primary driver of cardiac contractile failure;
yet, the cross talk between mitochondrial energetics and signaling regulation remains …

Efficient communication is essential in all layers of the biological chain. Cells exchange
information using a variety of signaling moieties, such as small molecules, proteins, and …