[HTML][HTML] Type 2 inflammation in asthma and other airway diseases

J Maspero, Y Adir, M Al-Ahmad… - ERJ open …, 2022 - Eur Respiratory Soc
Chronic inflammatory airway diseases, including asthma, chronic rhinosinusitis, eosinophilic
COPD and allergic rhinitis are a global health concern. Despite the coexistence of these …

[Translated article] Spanish COPD guidelines (GesEPOC) 2021: Updated pharmacological treatment of stable COPD

M Miravitlles, M Calle, J Molina, P Almagro… - Archivos de …, 2022 - Elsevier
Abstract The Spanish COPD Guidelines (GesEPOC) were first published in 2012, and since
then have undergone a series of updates incorporating new evidence on the diagnosis and …

Blood eosinophils and chronic obstructive pulmonary disease: a global initiative for chronic obstructive lung disease science committee 2022 review

D Singh, A Agusti, FJ Martinez, A Papi… - American journal of …, 2022 - atsjournals.org
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) published its first report
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …

Characterization of eosinophilic bronchiectasis: a European multicohort study

A Shoemark, M Shteinberg, A De Soyza… - American journal of …, 2022 - atsjournals.org
Rationale: Bronchiectasis is classically considered a neutrophilic disorder, but eosinophilic
subtypes have recently been described. Objectives: To use multiple datasets available …

Inflammatory endotypes in COPD

PJ Barnes - Allergy, 2019 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a major global health problem that is
poorly treated by current therapies as it has proved difficult to treat the underlying …

Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease

JH Yun, A Lamb, R Chase, D Singh, MM Parker… - Journal of allergy and …, 2018 - Elsevier
Background Eosinophilic airway inflammation in patients with chronic obstructive pulmonary
disease (COPD) is associated with exacerbations and responsivity to steroids, suggesting …

Chronic obstructive pulmonary disease biomarkers and their interpretation

RA Stockley, DMG Halpin, BR Celli… - American journal of …, 2019 - atsjournals.org
The pathology and impact of chronic obstructive pulmonary disease (COPD) results from an
abnormal inflammatory process resulting in tissue damage with ineffective repair in …

Blood eosinophil counts in clinical trials for chronic obstructive pulmonary disease

D Singh, M Bafadhel, CE Brightling… - American journal of …, 2020 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a complex condition with pathophysiology
and clinical characteristics that vary in presence and severity between patients (1). This …

New frontiers in the treatment of comorbid cardiovascular disease in chronic obstructive pulmonary disease

K Brassington, S Selemidis, S Bozinovski… - Clinical …, 2019 - portlandpress.com
Chronic obstructive pulmonary disease (COPD) is a disease characterised by persistent
airflow limitation that is not fully reversible and is currently the fourth leading cause of death …

Precision medicine in COPD: where are we and where do we need to go?

VK Sidhaye, K Nishida… - European Respiratory …, 2018 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) was the fourth leading cause of death
worldwide in 2015. Current treatments for patients ease discomfort and help decrease …