Akkermansia muciniphila as a Next-Generation Probiotic in Modulating Human Metabolic Homeostasis and Disease Progression: A Role Mediated by Gut–Liver …

H Jian, Y Liu, X Wang, X Dong, X Zou - International Journal of Molecular …, 2023 - mdpi.com
Appreciation of the importance of Akkermansia muciniphila is growing, and it is becoming
increasingly relevant to identify preventive and/or therapeutic solutions targeting gut–liver …

Aging and inflammation

A Singh, SH Schurman… - Cold Spring …, 2024 - perspectivesinmedicine.cshlp.org
Aging can be conceptualized as the progressive disequilibrium between stochastic damage
accumulation and resilience mechanisms that continuously repair that damage, which …

[HTML][HTML] Gut microbiota remodeling improves natural aging-related disorders through Akkermansia muciniphila and its derived acetic acid

J Ma, Z Liu, X Gao, Y Bao, Y Hong, X He, W Zhu… - Pharmacological …, 2023 - Elsevier
Accumulating evidence indicates gut microbiota contributes to aging-related disorders.
However, the exact mechanism underlying gut dysbiosis-related pathophysiological …

Secreted Akkermansia muciniphila threonyl-tRNA synthetase functions to monitor and modulate immune homeostasis

SM Kim, S Park, SH Hwang, EY Lee, JH Kim, GS Lee… - Cell host & …, 2023 - cell.com
Commensal bacteria are critically involved in the establishment of tolerance against
inflammatory challenges, the molecular mechanisms of which are just being uncovered. All …

Aging microbiota-gut-brain axis in stroke risk and outcome

P Honarpisheh, RM Bryan, LD McCullough - Circulation research, 2022 - ahajournals.org
The microbiota-gut-brain-axis (MGBA) is a bidirectional communication network between gut
microbes and their host. Many environmental and host-related factors affect the gut …

[HTML][HTML] Dysbiosis of gut microbiota from the perspective of the gut–brain axis: role in the provocation of neurological disorders

M Kandpal, O Indari, B Baral, S Jakhmola, D Tiwari… - Metabolites, 2022 - mdpi.com
The gut–brain axis is a bidirectional communication network connecting the gastrointestinal
tract and central nervous system. The axis keeps track of gastrointestinal activities and …

Therapeutics for neurodegenerative diseases by targeting the gut microbiome: from bench to bedside

YY Ma, X Li, JT Yu, YJ Wang - Translational Neurodegeneration, 2024 - Springer
The aetiologies and origins of neurodegenerative diseases, such as Alzheimer's disease
(AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and Huntington's …

High body temperature increases gut microbiota-dependent host resistance to influenza A virus and SARS-CoV-2 infection

M Nagai, M Moriyama, C Ishii, H Mori… - Nature …, 2023 - nature.com
Fever is a common symptom of influenza and coronavirus disease 2019 (COVID-19), yet its
physiological role in host resistance to viral infection remains less clear. Here, we …

The role of the probiotic Akkermansia muciniphila in brain functions: insights underpinning therapeutic potential

R Xu, Y Zhang, S Chen, Y Zeng, X Fu… - Critical reviews in …, 2023 - Taylor & Francis
The role of Akkermansia muciniphila, one of the most abundant microorganisms of the
intestinal microbiota, has been studied extensively in metabolic diseases, such as obesity …

[HTML][HTML] Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms

Y **ao, Y Feng, J Zhao, W Chen, W Lu - Journal of Advanced Research, 2024 - Elsevier
Background Population aging has become a primary global public health issue, and the
prevention of age-associated diseases and prolonging healthy life expectancies are of …