[HTML][HTML] Integration strategies of multi-omics data for machine learning analysis

M Picard, MP Scott-Boyer, A Bodein, O Périn… - Computational and …, 2021 - Elsevier
Increased availability of high-throughput technologies has generated an ever-growing
number of omics data that seek to portray many different but complementary biological …

Multi-omics data integration, interpretation, and its application

I Subramanian, S Verma, S Kumar… - … and biology insights, 2020 - journals.sagepub.com
To study complex biological processes holistically, it is imperative to take an integrative
approach that combines multi-omics data to highlight the interrelationships of the involved …

Integrated omics: tools, advances and future approaches

BB Misra, C Langefeld, M Olivier… - Journal of molecular …, 2019 - jme.bioscientifica.com
With the rapid adoption of high-throughput omic approaches to analyze biological samples
such as genomics, transcriptomics, proteomics, and metabolomics, each analysis can …

missMDA: a package for handling missing values in multivariate data analysis

J Josse, F Husson - Journal of statistical software, 2016 - jstatsoft.org
We present the R package missMDA which performs principal component methods on
incomplete data sets, aiming to obtain scores, loadings and graphical representations …

Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke

J Montaner, L Ramiro, A Simats, S Tiedt… - Nature Reviews …, 2020 - nature.com
Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …

Dimension reduction techniques for the integrative analysis of multi-omics data

C Meng, OA Zeleznik, GG Thallinger… - Briefings in …, 2016 - academic.oup.com
State-of-the-art next-generation sequencing, transcriptomics, proteomics and other high-
throughput 'omics' technologies enable the efficient generation of large experimental data …

Multiple factor analysis: principal component analysis for multitable and multiblock data sets

H Abdi, LJ Williams, D Valentin - Wiley Interdisciplinary reviews …, 2013 - Wiley Online Library
Multiple factor analysis (MFA, also called multiple factorial analysis) is an extension of
principal component analysis (PCA) tailored to handle multiple data tables that measure …

NCBI GEO: archive for functional genomics data sets—10 years on

T Barrett, DB Troup, SE Wilhite, P Ledoux… - Nucleic acids …, 2010 - academic.oup.com
A decade ago, the Gene Expression Omnibus (GEO) database was established at the
National Center for Biotechnology Information (NCBI). The original objective of GEO was to …

A selective review of multi-level omics data integration using variable selection

C Wu, F Zhou, J Ren, X Li, Y Jiang, S Ma - High-throughput, 2019 - mdpi.com
High-throughput technologies have been used to generate a large amount of omics data. In
the past, single-level analysis has been extensively conducted where the omics …

Analytical platform for metabolome analysis of microbial cells using methyl chloroformate derivatization followed by gas chromatography–mass spectrometry

KF Smart, RBM Aggio, JR Van Houtte… - Nature protocols, 2010 - nature.com
This protocol describes an analytical platform for the analysis of intra-and extracellular
metabolites of microbial cells (yeast, filamentous fungi and bacteria) using gas …