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[HTML][HTML] Next-generation TB vaccines: progress, challenges, and prospects
L Zhuang, Z Ye, L Li, L Yang, W Gong - Vaccines, 2023 - mdpi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global
infectious disease and a leading cause of mortality worldwide. Currently, the only available …
infectious disease and a leading cause of mortality worldwide. Currently, the only available …
The immune epitope database and analysis resource in epitope discovery and synthetic vaccine design
The task of epitope discovery and vaccine design is increasingly reliant on bioinformatics
analytic tools and access to depositories of curated data relevant to immune reactions and …
analytic tools and access to depositories of curated data relevant to immune reactions and …
A transformer-based model to predict peptide–HLA class I binding and optimize mutated peptides for vaccine design
Human leukocyte antigen (HLA) can recognize and bind foreign peptides to present them to
specialized immune cells, then initiate an immune response. Computational prediction of the …
specialized immune cells, then initiate an immune response. Computational prediction of the …
IEDB-AR: immune epitope database—analysis resource in 2019
Abstract The Immune Epitope Database Analysis Resource (IEDB-AR, http://tools. iedb. org/)
is a companion website to the IEDB that provides computational tools focused on the …
is a companion website to the IEDB that provides computational tools focused on the …
Immunotherapy of non-Hodgkin's lymphoma with a defined ratio of CD8+ and CD4+ CD19-specific chimeric antigen receptor–modified T cells
CD19-specific chimeric antigen receptor (CAR)–modified T cells have antitumor activity in B
cell malignancies, but factors that affect toxicity and efficacy have been difficult to define …
cell malignancies, but factors that affect toxicity and efficacy have been difficult to define …
Predicting HLA class II antigen presentation through integrated deep learning
Accurate prediction of antigen presentation by human leukocyte antigen (HLA) class II
molecules would be valuable for vaccine development and cancer immunotherapies …
molecules would be valuable for vaccine development and cancer immunotherapies …
[HTML][HTML] Heterogeneous tumor-immune microenvironments among differentially growing metastases in an ovarian cancer patient
We present an exceptional case of a patient with high-grade serous ovarian cancer, treated
with multiple chemotherapy regimens, who exhibited regression of some metastatic lesions …
with multiple chemotherapy regimens, who exhibited regression of some metastatic lesions …
Contriving multi-epitope subunit of vaccine for COVID-19: immunoinformatics approaches
R Dong, Z Chu, F Yu, Y Zha - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …
Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity
SARS-CoV-2 variants that escape neutralization and potentially affect vaccine efficacy have
emerged. T cell responses play a role in protection from reinfection and severe disease, but …
emerged. T cell responses play a role in protection from reinfection and severe disease, but …
Subtractive proteomics to identify novel drug targets and reverse vaccinology for the development of chimeric vaccine against Acinetobacter baumannii
The emergence of drug-resistant Acinetobacter baumannii is the global health problem
associated with high mortality and morbidity. Therefore it is high time to find a suitable …
associated with high mortality and morbidity. Therefore it is high time to find a suitable …