Remote ischaemic preconditioning: underlying mechanisms and clinical application

DJ Hausenloy, DM Yellon - Cardiovascular research, 2008 - academic.oup.com
Remote ischaemic preconditioning (RIPC) represents a strategy for harnessing the body's
endogenous protective capabilities against the injury incurred by ischaemia and …

Remote ischemic preconditioning: a novel protective method from ischemia reperfusion injury—a review

N Tapuria, Y Kumar, MM Habib, MA Amara… - Journal of Surgical …, 2008 - Elsevier
BACKGROUND: Restoration of blood supply to an organ after a critical period of ischemia
results in parenchymal injury and dysfunction of the organ referred to as reperfusion injury …

The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote …

I Andreadou, EK Iliodromitis, T Rassaf… - British journal of …, 2015 - Wiley Online Library
Ischaemic heart disease is one of the leading causes of morbidity and mortality worldwide.
The development of cardioprotective therapeutic agents remains a partly unmet need and a …

Translation of remote ischaemic preconditioning into clinical practice

RK Kharbanda, TT Nielsen, AN Redington - The Lancet, 2009 - thelancet.com
Reduction of the burden of ischaemia-reperfusion injury is the aim of most treatments for
cardiovascular and cerebrovascular disease. Although many strategies have proven benefit …

Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction

PD Addison, PC Neligan… - American Journal …, 2003 - journals.physiology.org
The aim of this study was to investigate the efficacy and mechanism of action of a
noninvasive remote ischemic preconditioning (IPC) technique for the protection of multiple …

Remote preconditioning by infrarenal occlusion of the aorta protects the heart from infarction: a newly identified non-neuronal but PKC-dependent pathway

C Weinbrenner, M Nelles, N Herzog… - Cardiovascular …, 2002 - academic.oup.com
Background: Ischemic preconditioning is a powerful mechanism in reducing infarct size of
the heart. Protection can be performed either by an ischemic stimulus of the heart itself or by …

Remote preconditioning by infrarenal aortic occlusion is operative via δ1-opioid receptors and free radicals in vivo in the rat heart

C Weinbrenner, F Schulze, L Sárváry… - Cardiovascular …, 2004 - academic.oup.com
Background: Ischemic preconditioning (PC) is a powerful mechanism in reducing infarct size
of the heart. Protection can be performed either by an ischemic stimulus of the heart itself or …

Pretreatment with the nitric oxide donor SNAP or nerve transection blocks humoral preconditioning by remote limb ischemia or intra-arterial adenosine

T Steensrud, J Li, X Dai, C Manlhiot… - American Journal …, 2010 - journals.physiology.org
We have previously shown that remote ischemic preconditioning (rIPC) by transient limb
ischemia leads to the release of a circulating factor (s) that induces potent myocardial …

Protocols and mechanisms for remote ischemic preconditioning: a novel method for reducing ischemia reperfusion injury

S Kanoria, R Jalan, AM Seifalian, R Williams… - …, 2007 - journals.lww.com
Ischemia reperfusion injury (IRI) results in damage to local and remote organs. Remote
ischemic preconditioning (RIPC) is a strategy to protect against IRI by inducing a prior brief …

Transient limb ischemia induces remote preconditioning in liver among rats: the protective role of heme oxygenase-1

IR Lai, KJ Chang, CF Chen, HW Tsai - Transplantation, 2006 - journals.lww.com
Background. We have reported the protective role of heme oxygenase-1 (HO-1) in the
mechanism of hypoxic preconditioning. We wish to investigate the role of HO-1 in remote …