The immune response during acute HIV-1 infection: clues for vaccine development
AJ McMichael, P Borrow, GD Tomaras… - Nature Reviews …, 2010 - nature.com
The early immune response to HIV-1 infection is likely to be an important factor in
determining the clinical course of disease. Recent data indicate that the HIV-1 quasispecies …
determining the clinical course of disease. Recent data indicate that the HIV-1 quasispecies …
Staphylococcal and streptococcal superantigen exotoxins
AR Spaulding, W Salgado-Pabón… - Clinical microbiology …, 2013 - Am Soc Microbiol
This review begins with a discussion of the large family of Staphylococcus aureus and beta-
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …
Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
Inflammation in HIV infection is predictive of non-AIDS morbidity and death, higher set point
plasma virus load and virus acquisition; thus, therapeutic agents are in development to …
plasma virus load and virus acquisition; thus, therapeutic agents are in development to …
Genital inflammation and the risk of HIV acquisition in women
Abstract Background. Women in Africa, especially young women, have very high human
immunodeficiency virus (HIV) incidence rates that cannot be fully explained by behavioral …
immunodeficiency virus (HIV) incidence rates that cannot be fully explained by behavioral …
HIV‐associated chronic immune activation
Systemic chronic immune activation is considered today as the driving force of CD 4+ T‐cell
depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune …
depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune …
Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis
M Aldunate, D Srbinovski, AC Hearps… - Frontiers in …, 2015 - frontiersin.org
Lactic acid and short chain fatty acids (SCFAs) produced by vaginal microbiota have
reported antimicrobial and immune modulatory activities indicating their potential as …
reported antimicrobial and immune modulatory activities indicating their potential as …
Targeting early infection to prevent HIV-1 mucosal transmission
AT Haase - Nature, 2010 - nature.com
Measures to prevent sexual mucosal transmission of human immunodeficiency virus (HIV)-1
are urgently needed to curb the growth of the acquired immunodeficiency syndrome (AIDS) …
are urgently needed to curb the growth of the acquired immunodeficiency syndrome (AIDS) …
HIV transmission
HIV-1 is transmitted by sexual contact across mucosal surfaces, by maternal-infant
exposure, and by percutaneous inoculation. For reasons that are still incompletely …
exposure, and by percutaneous inoculation. For reasons that are still incompletely …
Phenotypic properties of transmitted founder HIV-1
Defining the virus–host interactions responsible for HIV-1 transmission, including the
phenotypic requirements of viruses capable of establishing de novo infections, could be …
phenotypic requirements of viruses capable of establishing de novo infections, could be …
Nonhuman primate models of human viral infections
Humans have a close phylogenetic relationship with nonhuman primates (NHPs) and share
many physiological parallels, such as highly similar immune systems, with them. Importantly …
many physiological parallels, such as highly similar immune systems, with them. Importantly …