Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center
Abstract The Knight-Alzheimer Disease Research Center (Knight-ADRC) at Washington
University in St. Louis has pioneered and led worldwide seminal studies that have …
University in St. Louis has pioneered and led worldwide seminal studies that have …
CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease
In this high-throughput proteomic study of autosomal dominant Alzheimer's disease (ADAD),
we sought to identify early biomarkers in cerebrospinal fluid (CSF) for disease monitoring …
we sought to identify early biomarkers in cerebrospinal fluid (CSF) for disease monitoring …
SMOC1 colocalizes with Alzheimer's disease neuropathology and delays Aβ aggregation
K Balcomb, C Johnston, T Kavanagh, D Leitner… - Acta …, 2024 - Springer
SMOC1 has emerged as one of the most significant and consistent new biomarkers of early
Alzheimer's disease (AD). Recent studies show that SMOC1 is one of the earliest changing …
Alzheimer's disease (AD). Recent studies show that SMOC1 is one of the earliest changing …
Benchmarking of a multi‐biomarker low‐volume panel for Alzheimer's disease and related dementia research
INTRODUCTION In the research setting, obtaining accurate established biomarker
measurements and maximizing use of the precious samples is key. Accurate technologies …
measurements and maximizing use of the precious samples is key. Accurate technologies …
Multi-omic ADNI CSF and plasma data integration identifies distinct metabolic transitions in disease progression in Alzheimer's Disease
T Paterson, J Rohrs, TJ Hohman, M Mapstone… - bioRxiv, 2024 - biorxiv.org
Age and APOE allele status are the two greatest risk factors for Alzheimer's disease, with
microglial processing, recycling of debris and cholesterol transport emerging as other key …
microglial processing, recycling of debris and cholesterol transport emerging as other key …
[PDF][PDF] Genetic and multi-omic resources for alzheimer disease and related dementia from the Knight alzheimer Disease Research Center
The Knight-Alzheimer Disease Research Center (Knight-ADRC) at Washington University in
St. Louis has pioneered and led worldwide seminal studies that have expanded our clinical …
St. Louis has pioneered and led worldwide seminal studies that have expanded our clinical …