A review of the diagnosis, prevention, and treatment methods of inflammatory bowel disease

SS Seyedian, F Nokhostin… - Journal of medicine and …, 2019 - pmc.ncbi.nlm.nih.gov
Ulcerative colitis (UC) and Crohn's disease (CD) are classified as chronic inflammatory
bowel diseases (IBD) which have similar symptoms and lead to digestive disorders and …

A comprehensive review and update on Crohn's disease

M Gajendran, P Loganathan, AP Catinella… - Disease-a-month, 2018 - Elsevier
The term inflammatory bowel disease (IBD) refers principally to two major categories of
chronic relapsing inflammatory intestinal disorders: Crohn's disease (CD) and ulcerative …

ACG clinical guideline: management of Crohn's disease in adults

GR Lichtenstein, EV Loftus, KL Isaacs… - Official journal of the …, 2018 - journals.lww.com
Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic,
immunologic, and environmental influences. The incidence of Crohn's disease has steadily …

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo …

W Hueber, BE Sands, S Lewitzky… - Gut, 2012 - gut.bmj.com
Objective The authors tested whether the anti-interleukin (IL)-17A monoclonal antibody
secukinumab was safe and effective for the treatment of active Crohn's disease. Design In a …

Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 2: current management

A Dignass, JO Lindsay, A Sturm… - Journal of Crohn's …, 2012 - academic.oup.com
When deciding the appropriate treatment strategy for active ulcerative colitis one should
consider the activity, distribution (proctitis, left-sided, extensive 1), and pattern of disease …

Mucosal healing in inflammatory bowel diseases: a systematic review

MF Neurath, SPL Travis - Gut, 2012 - gut.bmj.com
Recent studies have identified mucosal healing on endoscopy as a key prognostic
parameter in the management of inflammatory bowel diseases (IBD), thus highlighting the …

Prebiotic effects: metabolic and health benefits

M Roberfroid, GR Gibson, L Hoyles… - British Journal of …, 2010 - cambridge.org
The different compartments of the gastrointestinal tract are inhabited by populations of micro-
organisms. By far the most important predominant populations are in the colon where a true …

Infliximab, azathioprine, or combination therapy for Crohn's disease

JF Colombel, WJ Sandborn, W Reinisch… - New England journal …, 2010 - Mass Medical Soc
Background The comparative efficacy and safety of infliximab and azathioprine therapy
alone or in combination for Crohn's disease are unknown. Methods In this randomized …

Guidelines for the management of inflammatory bowel disease in adults

C Mowat, A Cole, AL Windsor, T Ahmad, I Arnott… - Gut, 2011 - gut.bmj.com
The management of inflammatory bowel disease represents a key component of clinical
practice for members of the British Society of Gastroenterology (BSG). There has been …

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1958 Birth Cohort Controls Jones Richard W. 18 … - Nature, 2007 - nature.com
There is increasing evidence that genome-wide association (GWA) studies represent a
powerful approach to the identification of genes involved in common human diseases. We …