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Deciphering the impact of genomic variation on function
Code of Conduct Committee (alphabetical by last name … - Nature, 2024 - nature.com
Our genomes influence nearly every aspect of human biology—from molecular and cellular
functions to phenotypes in health and disease. Studying the differences in DNA sequence …
functions to phenotypes in health and disease. Studying the differences in DNA sequence …
Graph machine learning for integrated multi-omics analysis
Multi-omics experiments at bulk or single-cell resolution facilitate the discovery of hypothesis-
generating biomarkers for predicting response to therapy, as well as aid in uncovering …
generating biomarkers for predicting response to therapy, as well as aid in uncovering …
JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
Abstract JASPAR (https://jaspar. elixir. no/) is a widely-used open-access database
presenting manually curated high-quality and non-redundant DNA-binding profiles for …
presenting manually curated high-quality and non-redundant DNA-binding profiles for …
LIANA+ provides an all-in-one framework for cell–cell communication inference
The growing availability of single-cell and spatially resolved transcriptomics has led to the
development of many approaches to infer cell–cell communication, each capturing only a …
development of many approaches to infer cell–cell communication, each capturing only a …
Federated learning for healthcare applications
Due to the fast advancement of artificial intelligence (AI), centralized-based models have
become critical for healthcare tasks like in medical image analysis and human behavior …
become critical for healthcare tasks like in medical image analysis and human behavior …
An open source knowledge graph ecosystem for the life sciences
Translational research requires data at multiple scales of biological organization.
Advancements in sequencing and multi-omics technologies have increased the availability …
Advancements in sequencing and multi-omics technologies have increased the availability …
Drugst. One—a plug-and-play solution for online systems medicine and network-based drug repurposing
In recent decades, the development of new drugs has become increasingly expensive and
inefficient, and the molecular mechanisms of most pharmaceuticals remain poorly …
inefficient, and the molecular mechanisms of most pharmaceuticals remain poorly …
Revolutionizing immune research with organoid-based co-culture and chip systems
The intertwined interactions various immune cells have with epithelial cells in our body
require sophisticated experimental approaches to be studied. Due to the limitations of …
require sophisticated experimental approaches to be studied. Due to the limitations of …
Molecular causality in the advent of foundation models
Correlation is not causation: this simple and uncontroversial statement has far-reaching
implications. Defining and applying causality in biomedical research has posed significant …
implications. Defining and applying causality in biomedical research has posed significant …
LIANA+: an all-in-one cell-cell communication framework
The growing availability of single-cell and spatially-resolved transcriptomics has led to the
rapidly growing popularity of methods to infer cell-cell communication. Many approaches …
rapidly growing popularity of methods to infer cell-cell communication. Many approaches …