Biomarkers: Promising and valuable tools towards diagnosis, prognosis and treatment of Covid-19 and other diseases

A Bodaghi, N Fattahi, A Ramazani - Heliyon, 2023 - cell.com
The use of biomarkers as early warning systems in the evaluation of disease risk has
increased markedly in the last decade. Biomarkers are indicators of typical biological …

Review of recent developments in GC–MS approaches to metabolomics-based research

DJ Beale, FR Pinu, KA Kouremenos, MM Poojary… - Metabolomics, 2018 - Springer
Background Metabolomics aims to identify the changes in endogenous metabolites of
biological systems in response to intrinsic and extrinsic factors. This is accomplished …

Interactions between medical plant-derived bioactive compounds: focus on antimicrobial combination effects

N Vaou, E Stavropoulou, C Voidarou, Z Tsakris… - Antibiotics, 2022 - mdpi.com
It is accepted that the medicinal use of complex mixtures of plant-derived bioactive
compounds is more effective than purified bioactive compounds due to beneficial …

Microbial biodiversity and bioremediation assessment through omics approaches

H Chandran, M Meena, K Sharma - Frontiers in Environmental …, 2020 - frontiersin.org
Industrialization, population burst, and changing lifestyles have resulted in the genesis of
non-degradable pollutants languishing the environment and human health. Biological …

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

WB Dunn, DI Broadhurst, HJ Atherton… - Chemical society …, 2011 - pubs.rsc.org
The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …

Global chemical analysis of biology by mass spectrometry

AA Aksenov, R da Silva, R Knight, NP Lopes… - Nature Reviews …, 2017 - nature.com
Mass spectrometry instruments measure the mass to charge ratio of ions, from which we
infer the molecular structures. They are key tools for investigating the incredibly diverse …

Metabolomics: a global biochemical approach to drug response and disease

R Kaddurah-Daouk, BS Kristal… - Annu. Rev. Pharmacol …, 2008 - annualreviews.org
Metabolomics is the study of metabolism at the global level. This rapidly develo** new
discipline has important potential implications for pharmacologic science. The concept that …

Targeted metabolomics for biomarker discovery

WJ Griffiths, T Koal, Y Wang, M Kohl… - Angewandte Chemie …, 2010 - Wiley Online Library
Metabolomics is a truly interdisciplinary field of science, which combines analytical
chemistry, platform technology, mass spectrometry, and NMR spectroscopy with …

Analysis of intracellular metabolites from microorganisms: quenching and extraction protocols

FR Pinu, SG Villas-Boas, R Aggio - Metabolites, 2017 - mdpi.com
Sample preparation is one of the most important steps in metabolome analysis. The
challenges of determining microbial metabolome have been well discussed within the …

Towards quantitative metabolomics of mammalian cells: development of a metabolite extraction protocol

S Dietmair, NE Timmins, PP Gray, LK Nielsen… - Analytical …, 2010 - Elsevier
Metabolomics aims to quantify all metabolites within an organism, thereby providing
valuable insight into the metabolism of cells. To study intracellular metabolites, they are first …