Air pollution and lung function in children

E Garcia, MB Rice, DR Gold - Journal of Allergy and Clinical Immunology, 2021 - Elsevier
In this narrative review, we summarize the literature and provide updates on recent studies
of air pollution exposures and child lung function and lung function growth. We include …

[HTML][HTML] Systematic review of ozone effects on human lung function, 2013 through 2020

SM Holm, JR Balmes - Chest, 2022 - Elsevier
Background Ozone effects on lung function are particularly important to understand in the
context of the air pollution-health outcomes epidemiologic literature, given the complex …

Addressing disparities in lung cancer screening eligibility and healthcare access. An official American Thoracic Society statement

MP Rivera, HA Katki, NT Tanner, M Triplette… - American journal of …, 2020 - atsjournals.org
Background: There are well-documented disparities in lung cancer outcomes across
populations. Lung cancer screening (LCS) has the potential to reduce lung cancer mortality …

Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium

SP Sajuthi, P DeFord, Y Li, ND Jackson… - Nature …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, an emerging
virus that utilizes host proteins ACE2 and TMPRSS2 as entry factors. Understanding the …

Effects of long-term exposure to traffic-related air pollution on lung function in children

ES Schultz, AA Litonjua, E Melén - Current allergy and asthma reports, 2017 - Springer
Lung function in early life has been shown to be an important predictor for peak lung
function in adults and later decline. Reduced lung function per se is associated with …

Single-cell and population transcriptomics reveal pan-epithelial remodeling in type 2-high asthma

ND Jackson, JL Everman, M Chioccioli, L Feriani… - Cell reports, 2020 - cell.com
The type 2 cytokine-high asthma endotype (T2H) is characterized by IL-13-driven mucus
obstruction of the airways. To further investigate this incompletely understood pathobiology …

Urban residence, neighborhood poverty, race/ethnicity, and asthma morbidity among children on Medicaid

CA Keet, EC Matsui, MC McCormack… - Journal of Allergy and …, 2017 - Elsevier
Background Although poor-urban (inner-city) areas are thought to have high asthma
prevalence and morbidity, we recently found that inner cities do not have higher prevalent …

Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology

SP Sajuthi, JL Everman, ND Jackson, B Saef… - Nature …, 2022 - nature.com
To identify genetic determinants of airway dysfunction, we performed a transcriptome-wide
association study for asthma by combining RNA-seq data from the nasal airway epithelium …

Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium

SP Sajuthi, P DeFord, ND Jackson, MT Montgomery… - Biorxiv, 2020 - pmc.ncbi.nlm.nih.gov
Coronavirus disease 2019 (COVID-19) outcomes vary from asymptomatic infection to death.
This disparity may reflect different airway levels of the SARS-CoV-2 receptor, ACE2, and the …

News on climate change, air pollution, and allergic triggers of asthma

L Cecchi, I Annesi-Maesano… - Journal of …, 2018 - hal.sorbonne-universite.fr
Résumé The rising frequency of obstructive respiratory diseases during recent years, in
particular allergic asthma, can be partially explained by changes in the environment, with …