With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …

Peptide molecules have design flexibility, self-assembly ability, high biocompatibility, good
biodegradability, and easy functionalization, which promote their applications as versatile …

The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

After myocardial infarction (MI), sustained ischemic events induce pathological
microenvironments characterized by ischemia‐hypoxia, oxidative stress, inflammatory …

Macrophage-assisted immunomodulation is an alternative strategy in tissue engineering,
wherein the interplay between pro-inflammatory and anti-inflammatory macrophage cells …

Programmed cell death protein-1 (PD-1) checkpoint immunotherapy efficacy remains
unpredictable in glioblastoma (GBM) patients due to the genetic heterogeneity and …

The extracellular matrix (ECM) plays critical roles in cytoskeletal support, biomechanical
transduction and biochemical signal transformation. Tumor-associated macrophage (TAM) …

The immune system protects organisms against endogenous and exogenous harm and
plays a key role in tissue development, repair and regeneration. Traditional …

Inflammation plays a central role in wound healing following injury or disease and is
mediated by a precise cascade of cellular and molecular events. Unresolved inflammatory …

The rational design of hydrogel materials to modulate the immune microenvironment has
emerged as a pivotal approach in expediting tissue repair and regeneration. Within the …