Genetics and epigenetics in asthma
P Ntontsi, A Photiades, E Zervas, G Xanthou… - International journal of …, 2021 - mdpi.com
Asthma is one of the most common respiratory disease that affects both children and adults
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …
Human genetics and malaria resistance
Malaria has been the pre-eminent cause of early mortality in many parts of the world
throughout much of the last five thousand years and, as a result, it is the strongest force for …
throughout much of the last five thousand years and, as a result, it is the strongest force for …
Evaluating the promise of inclusion of African ancestry populations in genomics
AR Bentley, SL Callier, CN Rotimi - NPJ genomic medicine, 2020 - nature.com
The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …
known, and the resultant scientific and ethical limitations are becoming increasingly …
Characterizing the genetic architecture of Parkinson's disease in Latinos
Objective This work was undertaken in order to identify Parkinson's disease (PD) risk
variants in a Latino cohort, to describe the overlap in the genetic architecture of PD in …
variants in a Latino cohort, to describe the overlap in the genetic architecture of PD in …
Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations
Asthma is a complex disease with striking disparities across racial and ethnic groups.
Despite its relatively high burden, representation of individuals of African ancestry in asthma …
Despite its relatively high burden, representation of individuals of African ancestry in asthma …
Building a vertically integrated genomic learning health system: The biobank at the Colorado Center for Personalized Medicine
Precision medicine initiatives across the globe have led to a revolution of repositories linking
large-scale genomic data with electronic health records, enabling genomic analyses across …
large-scale genomic data with electronic health records, enabling genomic analyses across …
Clinical implementation of pharmacogenomics via a health system-wide research biobank: the University of Colorado experience
In recent years, the genomics community has witnessed the growth of large research
biobanks, which collect DNA samples for research purposes. Depending on how and where …
biobanks, which collect DNA samples for research purposes. Depending on how and where …
Heterogeneous genetic architectures of prostate cancer susceptibility in sub-Saharan Africa
Men of African descent have the highest prostate cancer incidence and mortality rates, yet
the genetic basis of prostate cancer in African men has been understudied. We used …
the genetic basis of prostate cancer in African men has been understudied. We used …
Genome-wide association studies of severe P. falciparum malaria susceptibility: progress, pitfalls and prospects
D Damena, A Denis, L Golassa, ER Chimusa - BMC medical genomics, 2019 - Springer
Background P. falciparum malaria has been recognized as one of the prominent
evolutionary selective forces of human genome that led to the emergence of multiple host …
evolutionary selective forces of human genome that led to the emergence of multiple host …
Polygenic prediction of atopic dermatitis improves with atopic training and filaggrin factors
Background While numerous genetic loci associated with atopic dermatitis (AD) have been
discovered, to date, work leveraging the combined burden of AD risk variants across the …
discovered, to date, work leveraging the combined burden of AD risk variants across the …