The eukaryotic transcription apparatus synthesizes a staggering diversity of RNA molecules.
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …

Poly (A) tails are non-templated additions of adenosines at the 3′ ends of most eukaryotic
mRNAs. In the nucleus, these RNAs are co-transcriptionally cleaved at a poly (A) site and …

RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

Deadenylation generally constitutes the first and pivotal step in eukaryotic messenger RNA
decay. Despite its importance in posttranscriptional regulations, the kinetics of …

RNase P is the essential activity that performs the 5′ maturation of transfer RNA (tRNA)
precursors. Beyond the ancestral form of RNase P containing a ribozyme, protein-only …

Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …

The cellular response to changes in the surrounding environment and to stress requires the
coregulation of gene networks aiming to conserve energy and resources. This is often …

Abstract The RNA polymerase III (Pol III) transcriptome is universally comprised of short,
highly structured noncoding RNA (ncRNA). Through RNA–protein interactions, the Pol III …

Alternative splicing (AS) serves as a pivotal mechanism in transcriptional regulation,
engendering transcript diversity, and modifications in protein structure and functionality …

Telomerase is unique among the reverse transcriptases in containing a noncoding RNA
(known as telomerase RNA (TER)) that includes a short template that is used for the …