An update of anthraquinone derivatives emodin, diacerein, and catenarin in diabetes

M Martorell, N Castro, M Victoriano… - Evidence‐Based …, 2021 - Wiley Online Library
Diabetes is part of metabolic diseases and is characterized by high blood sugar levels over
a prolonged period as result of an insulin‐deficient production or an inappropriate response …

Advances in the study of emodin: an update on pharmacological properties and mechanistic basis

Q Zheng, S Li, X Li, R Liu - Chinese Medicine, 2021 - Springer
Abstract Rhei Radix et Rhizoma, also known as rhubarb or Da Huang, has been widely
used as a spice and as traditional herbal medicine for centuries, and is currently marketed in …

Salidroside inhibits inflammation through PI3K/Akt/HIF signaling after focal cerebral ischemia in rats

Y Wei, H Hong, X Zhang, W Lai, Y Wang, K Chu… - Inflammation, 2017 - Springer
Salidroside is being investigated for its therapeutic potential in stroke because it is
neuroprotective over an extended therapeutic window of time. In the present study, we …

Cichorium pumilum Jacq Extract Inhibits LPS-Induced Inflammation via MAPK Signaling Pathway and Protects Rats From Hepatic Fibrosis Caused by Abnormalities …

C Han, X Wu, N Zou, Y Zhang, J Yuan, Y Gao… - Frontiers in …, 2021 - frontiersin.org
The development of liver fibrosis is closely related to the gut microbiota, and the “gut-liver
axis” is the most important connection between the two. ethyl acetate extract of Cichorium …

Inhibition of complement drives increase in early growth response proteins and neuroprotection mediated by salidroside after cerebral ischemia

W Lai, XL **e, X Zhang, Y Wang, K Chu, J Brown… - Inflammation, 2018 - Springer
Salidroside is neuroprotective across a wide therapeutic time-window after cerebral
ischemia-reperfusion injury (IRI). Here, we investigated the role of complement in mediating …

Toll‐like receptor 4‐dependent innate immune responses are mediated by intracrine corticosteroids and activation of glycogen synthase kinase‐3β in astrocytes

W Lai, S Huang, J Liu, B Zhou, Z Yu… - The FASEB …, 2024 - Wiley Online Library
Reactive astrocytes are important pathophysiologically and synthesize neurosteroids. We
observed that LPS increased immunoreactive TLR4 and key steroidogenic enzymes in …

[PDF][PDF] How much we know about the attenuation of insulin signaling in the adipose tissue caused by glucocorticoid treatment?

A Rafacho, EA Nunes, S Bordin - Inflamm Cell Signal, 2015 - researchgate.net
Glucocorticoid (GC) hormone exerts numerous physiological roles that include modulation
of immune, nervous, cardiovascular and metabolic systems. Synthetic GCs such as …

[HTML][HTML] 红景天苷调控 PI3K/Akt 信号通路对 LPS 诱导的 BV2 小胶质细胞的抗炎作用

杨泽霖, 黄鑫, 刘俊杰, 唐宇恒, 洪海棉, 南丽红… - 2019 - html.rhhz.net
目的探讨红景天苷对脂多糖(LPS) 诱导的BV2 小胶质细胞的抗炎作用及其机制. 方法建立LPS
诱导BV2 小胶质细胞损伤模型. 经不同浓度的红景天苷作用后, qPCR 法检测细胞因子IL-6, IL …

[PDF][PDF] An Update of Anthraquinone Derivatives Emodin, Diacerein, and Catenarin in Diabetes

S Tejada, S Vitalini, R Pezzani, A Sureda - 2021 - academia.edu
Diabetes is part of metabolic diseases and is characterized by high blood sugar levels over
a prolonged period as result of an insulin-deficient production or an inappropriate response …

[PDF][PDF] Journal of Natural Products and Resources

R Sharma, K Hem, D Sharma, VP Singh, NK Singh - jacsdirectory.com
The plant Inula racemosa Hook. F.(Asteraceae), usually known as Pushkarmula, found
almost in all parts of the India ascending to an altitude of 4,200 m from the sea level. I …