Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …

Abstract Poly (amidoamine)(PAMAM) dendrimers are well-defined, highly branched
macromolecules with numerous active amine groups on the surface. Because of their …

The last decade has witnessed enormous research focused on cationic polymers. Cationic
polymers are the subject of intense research as non-viral gene delivery systems, due to their …

More than 40 nanomedicines are already in routine clinical use with a growing number
following in preclinical and clinical development. The therapeutic objectives are often …

In this study, novel folate-receptor-targeted polyamidoamine (PAMAM) dendrimer functional
mesoporous silica-coated magnetic nanoparticles were prepared for drug delivery agents …

Poly (amidoamine) s (PAAs) are a family of synthetic polymers obtained by stepwise
polyaddition of prim‐or sec‐amines to bisacrylamides. Nearly all conceivable …

Glioblastoma (GBM) is the most aggressive form of brain cancer, with a dismal prognosis
and extremely low percentage of survivors. Novel therapies are in dire need to improve the …

Worldwide, the cancer appeared as one of the most leading cause of morbidity and
mortality. Among the various cancer types, brain tumors are most life threatening with low …

The discovery of small RNA molecules with the capacity to regulate messenger RNA
(mRNA) stability and translation (and consequently protein synthesis) has revealed an …

Current malaria therapeutics demands strategies able to selectively deliver drugs to
Plasmodium-infected red blood cells (pRBCs) in order to limit the appearance of parasite …