The interaction between host and external environment mainly occurs in the gastrointestinal
tract, where the mucosal barrier has a critical role in many physiologic functions ranging …

ABSTRACT L-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in
mammalian and microbial organisms. Thus, L-arg participates as precursor of multiple …

Melatonin has been shown to improve lipid metabolism and gut microbiota communities in
animals and humans; however, it remains to know whether melatonin prevents obesity …

Altered intestinal permeability plays a role in many pathological conditions. Intestinal
permeability is a component of the intestinal barrier. This barrier is a dynamic interface …

Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Oxidative stress and intestinal inflammation are main pathological features of ulcerative
colitis (UC). Ferroptosis, characterized by iron accumulation and lipid peroxidation, is closely …

Weaning imposes simultaneous stress, resulting in reduced feed intake, and growth rate,
and increased morbidity and mortality of weaned pigs. Weaning impairs the intestinal …

Intestine is always exposed to external environment and intestinal microorganism; thus it is
more sensitive to dysfunction and dysbiosis, leading to intestinal inflammation, such as …

Although osteoarthritis (OA) has been traditionally regarded as a non-inflammatory disease,
reports increasingly suggest that it is inflammatory, at least in certain patients. OA patients …

The human body is in daily contact with potentially toxic and infectious substances in the
gastrointestinal tract (GIT). The GIT has the most significant load of antigens. The GIT can …