Strategies for improving the production of bio-based vanillin

Y Liu, L Sun, YX Huo, S Guo - Microbial Cell Factories, 2023 - Springer
Abstract Vanillin (4-hydroxy-3-methoxybenzaldehyde) is one of the most popular flavors with
wide applications in food, fragrance, and pharmaceutical industries. However, the high cost …

Biosystem design of Corynebacterium glutamicum for bioproduction

J Zha, Z Zhao, Z **ao, T Eng, A Mukhopadhyay… - Current Opinion in …, 2023 - Elsevier
Highlights•Corynebacterium glutamicum has been used for many applications beyond
amino acids.•Economical, high-quality genome assemblies foster development of non-type …

[HTML][HTML] Systems metabolic engineering upgrades Corynebacterium glutamicum to high-efficiency cis, cis-muconic acid production from lignin-based aromatics

F Weiland, N Barton, M Kohlstedt, J Becker… - Metabolic …, 2023 - Elsevier
Lignin displays a highly challenging renewable. To date, massive amounts of lignin,
generated in lignocellulosic processing facilities, are for the most part merely burned due to …

[HTML][HTML] Engineering 5-hydroxymethylfurfural (HMF) oxidation in Pseudomonas boosts tolerance and accelerates 2, 5-furandicarboxylic acid (FDCA) production

T Lechtenberg, B Wynands, N Wierckx - Metabolic Engineering, 2024 - Elsevier
Due to its tolerance properties, Pseudomonas has gained particular interest as host for
oxidative upgrading of the toxic aldehyde 5-hydroxymethylfurfural (HMF) into 2, 5 …

Minimal aromatic aldehyde reduction (MARE) yeast platform for engineering vanillin production

Q Mo, J Yuan - Biotechnology for Biofuels and Bioproducts, 2024 - Springer
Background Vanillin represents one of the most widely used flavoring agents in the world.
However, microbial synthesis of vanillin is hindered by the host native metabolism that could …

Functional food additives/ingredients production by engineered Corynebacterium glutamicum

K Cankar, NA Henke, VF Wendisch - Systems Microbiology and …, 2023 - Springer
Corynebacterium glutamicum is a microbial production host established in the industry 60
years ago. It is mainly used for production of feed and food amino acids. As C. glutamicum …

[HTML][HTML] Development of Corynebacterium glutamicum as a monoterpene production platform

BA Luckie, M Kashyap, AN Pearson, Y Chen, Y Liu… - Metabolic …, 2024 - Elsevier
Monoterpenes are commonly known for their role in the flavors and fragrances industry and
are also gaining attention for other uses like insect repellant and as potential renewable …

l-Serine Biosensor-Controlled Fermentative Production of l-Tryptophan Derivatives by Corynebacterium glutamicum

L Ferrer, M Elsaraf, M Mindt, VF Wendisch - Biology, 2022 - mdpi.com
Simple Summary l-tryptophan is an amino acid found in proteins. Its derivatives, such as
hydroxylated or halogenated l-tryptophans, find applications in the chemical and …

Para‑hydroxybenzaldehyde against transient focal cerebral ischemia in rats via mitochondrial preservation

T **ao, L Yang, P Chen, X Duan - Experimental and …, 2022 - spandidos-publications.com
Gastrodia elata (GE) Blume has been widely used for thousands of years to treat various
central and peripheral nervous disorders. P‑hydroxybenzaldehyde (PHBA) is a chemical …

Precision fermentation for producing food ingredients

S Cho, SY Jung, H Eun, SY Lee - Current Opinion in Food Science, 2024 - Elsevier
Highlights•Food ingredients can be produced through precision fermentation.•Progress in
systems metabolic engineering advanced precision fermentation.•Downstream processes …