Disclaimer This article is based on recommendations from the 12th WALT Congress, Nice,
October 3-6, 2018, and a follow-up review of the existing data and the clinical observations …

Despite the enthusiasm surrounding novel targeted agents and immunotherapies,
chemotherapy remains the mainstay treatment for most human malignancies, either alone or …

Background Mucositis is a significant toxicity of cancer therapy with numerous systemic
sequelae. The goal of this systematic review was to update the Multinational Association of …

The gut microbiota has emerged as a key modulator of cancer treatment responses in terms
of both efficacy and toxicity. This effect is clearly mediated by processes impacting the …

Chemotherapy kills fast-growing cells including gut stem cells. This affects all components of
the physical and functional intestinal barrier, ie, the mucus layer, epithelium, and immune …

Chemotherapy—induced gastrointestinal dysfunction is a common occurrence associated
with many different classes of chemotherapeutic agents. Gastrointestinal toxicity includes …

The gastrointestinal tract is particularly vulnerable to off-target effects of antineoplastic drugs
because intestinal epithelial cells proliferate rapidly and have a complex immunological …

Purpose Despite advances in personalizing the efficacy of cancer therapy, our ability to
identify patients at risk of severe treatment side effects and provide individualized supportive …

The side effects of cancer therapy continue to cause significant health and cost burden to the
patient, their friends and family, and governments. A major barrier in the way in which these …

Oral mucositis (OM) is one of the most common and debilitating oral complications of cancer
treatments including chemotherapy, radiotherapy, and hematopoietic stem cell …