Computational strategies for predicting free radical scavengers' protection against oxidative stress: where are we and what might follow?

A Galano, J Raúl Alvarez‐Idaboy - International Journal of …, 2019 - Wiley Online Library
Oxidative stress, which is frequently induced by an overproduction of free radicals (FR),
poses a high risk to human health. Thus, finding efficient strategies for scavenging FR is a …

Antioxidant and anti-collagenase activity of Hypericum hircinum L.

M Mandrone, B Lorenzi, A Venditti, L Guarcini… - Industrial Crops and …, 2015 - Elsevier
Hypericum hircinum L. is a shrub traditionally used in some Mediterranean areas as a
remedy for several diseases, mainly linked to the airway apparatus. In this work, an …

Computational study of benzothiazole derivatives for conformational, thermodynamic and spectroscopic features and their potential to act as antibacterials

A Mubarik, S Mahmood, N Rasool, MA Hashmi… - Crystals, 2022 - mdpi.com
Benzothiazole analogs are very interesting due to their potential activity against several
infections. In this research, five benzothiazole derivatives were studied using density …

[HTML][HTML] In vitro anti-inflammatory, antidiabetic, antibacterial, and in silico studies of Ferruginan A isolated from Olea ferruginea Royle (Oleaceae)

A Rauf, BO Aljohny, U Rashid, Y Anwar… - Saudi Pharmaceutical …, 2023 - Elsevier
Abstract Objective Traditionally, Olea ferruginea Royle (Oleaceae) has been used as a
painkiller and antidiabetic in various ailments. To provide a scientific background to this …

Chemical constituents from the leaves of Nephrolepis exaltata

AA Oyawaluja, BO Oyawaluja, F Aydogan, Z Ali… - Biochemical Systematics …, 2024 - Elsevier
Twenty-one compounds were isolated from the ethanol extract of the leaves of Nephrolepis
exaltata (Nephrolepidaceae), including one furan derivative (1), five phenol derivatives (2 …

Spectroscopic, computational DFT, in vitro, and molecular docking investigations of newly isolated 2, 3, 9, and 10-tetrahydroacridin-3-one from the methanolic extract …

P Kamalarajan, J Irshad Ahamed, R Priya… - Research on Chemical …, 2023 - Springer
The Gaussian09 program was studied by using the optimized molecular structure with
vibrational frequency assignments of 2, 3, 9, and 10 tetrahydroacridin-3-one (abbreviated as …

Investigation of Olea ferruginea Roylebark extracts for potential in vitroantidiabetic and anticancer effects

S Liaqat, M Islam, H Saeed, M Iqtedar… - Turkish Journal of …, 2021 - journals.tubitak.gov.tr
This study was conducted to investigate the physicochemical, phytochemical, in vitro
antidiabetic and anticancer potential of Olea ferruginea R bark. After extraction using …

Acridinedione as selective flouride ion chemosensor: a detailed spectroscopic and quantum mechanical investigation

N Iqbal, SA Ali, I Munir, S Khan, K Ayub, M Al-Rashida… - RSC …, 2018 - pubs.rsc.org
The use of small molecules as chemosensors for ion detection is rapidly gaining popularity
by virtue of the advantages it offers over traditional ion sensing methods. Herein we have …

Antioxidant and Cytotoxic Activity of a New Ferruginan A from Olea ferruginea: In Vitro and In Silico Studies

ZA Shah, AAH Mujawah, I Ullah, A Rauf… - Oxidative Medicine …, 2022 - Wiley Online Library
Studies of the ethyl acetate extract bark extract of Olea ferruginea led to the isolation of one
new compound Ferruginan A (1) in addition to two known compounds, Ferruginan (2) and …

Position impact of hydroxy groups on spectral, acid–base profiles and DNA interactions of several monohydroxy flavanones

E Łodyga-Chruścińska, A Kowalska-Baron… - Molecules, 2019 - mdpi.com
Structure-related biological activities of flavanones are still considered largely unexplored.
Since they exhibit various medicinal activities, it is intriguing to enter deeper into their …