This review summarizes the current knowledge on essential vitamins B1, B2, B3, and B5.
These B-complex vitamins must be taken from diet, with the exception of vitamin B3, that can …

The direct activation of inert saturated C–H bonds for selective functionalization has long
been a significant challenge in organic synthesis. The past few decades have witnessed the …

The importance of coenzyme A (CoA) as a carrier of acyl residues in cell metabolism is well
understood. Coenzyme A participates in more than 100 different catabolic and anabolic …

Multiple mitochondrial matrix enzymes playing key roles in metabolism require cofactors for
their action. Due to the high impermeability of the mitochondrial inner membrane, these …

Huntington's disease (HD) is a neurodegenerative disorder caused by an expanded CAG
repeat in exon 1 of the HTT gene. HD usually manifests in mid-life with loss of GABAergic …

Using a closed-head impact acceleration model of mild or severe traumatic brain injury
(mTBI or sTBI, respectively) in rats, we evaluated the effects of graded head impacts on the …

Pantothenate kinase–associated neurodegeneration (PKAN) is an incurable rare genetic
disorder of children and young adults caused by mutations in the PANK2 gene, which …

Many studies have been written on vitamin supplementation, fatty acid, and dementia, but
results are still under debate, and no definite conclusion has yet been drawn. Nevertheless …

Coenzyme A (CoA) is an essential cofactor in all living organisms. It is involved in a large
number of biochemical processes functioning either as an activator of molecules with …

Delivery mode is recognized as an important determinant of gut microbiota composition.
Vaginally delivered infants were colonized by maternal vaginal and fecal microbiota, while …