γδ T cells: origin and fate, subsets, diseases and immunotherapy
The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …
hyperactivation, highlights the potential of immune renormalization as a promising strategy …
Crohn's disease
M Dolinger, J Torres, S Vermeire - The Lancet, 2024 - thelancet.com
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract that might lead
to progressive bowel damage and disability. The exact cause of Crohn's disease is …
to progressive bowel damage and disability. The exact cause of Crohn's disease is …
Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries
Inflammatory bowel diseases (IBDs) are chronic disorders of the gastrointestinal tract with
the following two subtypes: Crohn's disease (CD) and ulcerative colitis (UC). To date, most …
the following two subtypes: Crohn's disease (CD) and ulcerative colitis (UC). To date, most …
The NLR family of innate immune and cell death sensors
Nucleotide-binding oligomerization domain (NOD)-like receptors, also known as nucleotide-
binding leucine-rich repeat receptors (NLRs), are a family of cytosolic pattern recognition …
binding leucine-rich repeat receptors (NLRs), are a family of cytosolic pattern recognition …
The NLR gene family: from discovery to present day
The mammalian NLR gene family was first reported over 20 years ago, although several
genes that were later grouped into the family were already known at that time. Although it is …
genes that were later grouped into the family were already known at that time. Although it is …
Neutrophils: from IBD to the gut microbiota
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract that results from dysfunction in innate and/or adaptive immune responses. Impaired …
tract that results from dysfunction in innate and/or adaptive immune responses. Impaired …
Interaction between microbiota and immunity in health and disease
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …
development and function includes multifold interactions in homeostasis and disease. The …
Inflammatory bowel diseases (IBD) and the microbiome—searching the crime scene for clues
Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial,
immunological, and genetic factors. Alterations in the gut microbiota have been associated …
immunological, and genetic factors. Alterations in the gut microbiota have been associated …
Crohn's disease
Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …
Implication of intestinal barrier dysfunction in gut dysbiosis and diseases
The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …