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[HTML][HTML] Can stemness and chemoresistance be therapeutically targeted via signaling pathways in ovarian cancer?
Ovarian cancer is the most lethal gynecological malignancy. Poor overall survival,
particularly for patients with high grade serous (HGS) ovarian cancer, is often attributed to …
particularly for patients with high grade serous (HGS) ovarian cancer, is often attributed to …
[HTML][HTML] The role of cancer stem cell markers in ovarian cancer
K Frąszczak, B Barczyński - Cancers, 2023 - mdpi.com
Simple Summary This manuscript focuses on cancer stem cells and the diagnostic potential
of selected biomarkers of these cells in ovarian cancers. Ovarian cancer has nonspecific …
of selected biomarkers of these cells in ovarian cancers. Ovarian cancer has nonspecific …
[HTML][HTML] Hyaluronic acid conjugated nanoparticle delivery of siRNA against TWIST reduces tumor burden and enhances sensitivity to cisplatin in ovarian cancer
SA Shahin, R Wang, SI Simargi, A Contreras… - … , Biology and Medicine, 2018 - Elsevier
TWIST protein is critical to development and is activated in many cancers. TWIST regulates
epithelial-mesenchymal transition, and is linked to angiogenesis, metastasis, cancer stem …
epithelial-mesenchymal transition, and is linked to angiogenesis, metastasis, cancer stem …
[HTML][HTML] RBM15‑mediating MDR1 mRNA m6A methylation regulated by the TGF‑β signaling pathway in paclitaxel‑resistant ovarian cancer
J Yuan, W Guan, X Li, F Wang… - … Journal of Oncology, 2023 - spandidos-publications.com
Ovarian cancer (OC) lacks effective biomarkers for diagnosis at an early stage and often
develops chemoresistance after the initial treatment at an advanced stage. RNA‑binding …
develops chemoresistance after the initial treatment at an advanced stage. RNA‑binding …
Nanoparticle delivery of siRNA against TWIST to reduce drug resistance and tumor growth in ovarian cancer models
CM Roberts, SA Shahin, W Wen, JB Finlay… - … , Biology and Medicine, 2017 - Elsevier
Epithelial ovarian cancer (EOC) is the most deadly gynecologic malignancy on account of its
late stage at diagnosis and frequency of drug resistant recurrences. Novel therapies to …
late stage at diagnosis and frequency of drug resistant recurrences. Novel therapies to …
CD44 expression predicts prognosis of ovarian cancer patients through promoting epithelial-mesenchymal transition (EMT) by regulating snail, ZEB1, and caveolin-1
J Zhou, Y Du, Y Lu, B Luan, C Xu, Y Yu… - Frontiers in oncology, 2019 - frontiersin.org
Objectives: CD44, a transmembrane glycoprotein, is involved in the generation of a stem cell
niche and maintaining stem cell quiescence. The aim of this study was to evaluate its …
niche and maintaining stem cell quiescence. The aim of this study was to evaluate its …
Clinicopathological and prognostic significance of cancer stem cell markers in ovarian cancer patients: Evidence from 52 studies
Y Tao, H Li, R Huang, D Mo, T Zeng, M Fang… - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: Relevant markers of cancer stem cells (CSCs) may serve as
commonly used biomarkers of ovarian cancer (OC). However, their actual …
commonly used biomarkers of ovarian cancer (OC). However, their actual …
[HTML][HTML] Metabolic plasticity in ovarian cancer stem cells
Ovarian Cancer is the fifth most common cancer in females and remains the most lethal
gynecological malignancy as most patients are diagnosed at late stages of the disease …
gynecological malignancy as most patients are diagnosed at late stages of the disease …
CD44 as a cancer stem cell marker and its prognostic value in patients with ovarian carcinoma
A Bartakova, K Michalova, J Presl… - Journal of Obstetrics …, 2018 - Taylor & Francis
The aim of our study was to clarify whether the CD44 adhesion molecule as a cancer stem
cell marker could also serve as a prognostic factor in patients with epithelial ovarian cancer …
cell marker could also serve as a prognostic factor in patients with epithelial ovarian cancer …
Effects of CD44 and E‑cadherin overexpression on the proliferation, adhesion and invasion of ovarian cancer cells
M Mao, X Zheng, B **, F Zhang… - Experimental and …, 2017 - spandidos-publications.com
CD44 is a prognostic indicator of shorter survival time in ovarian cancer. E‑cadherin
fragmentation promotes the progression of ovarian cancer. However, the effects of CD44 …
fragmentation promotes the progression of ovarian cancer. However, the effects of CD44 …