Sex, glia, and development: interactions in health and disease

JM Schwarz, SD Bilbo - Hormones and behavior, 2012 - Elsevier
This article is part of a Special Issue “Neuroendocrine-Immune Axis in Health and Disease.”
Microglia and astrocytes are the primary immune cells within the central nervous system …

Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine

MA Sánchez-Garrido, D García-Galiano… - Human …, 2022 - academic.oup.com
BACKGROUND According to the Developmental Origins of Health and Disease (DOHaD)
hypothesis, environmental changes taking place during early maturational periods may alter …

Evidence that elevation of maternal somatic cell count could lead to production of offspring with inferior reproductive and productive performance in dairy cows during …

H Sadeghi, F Gharagozlou, M Vojgani, E Mobedi… - Theriogenology, 2023 - Elsevier
Although the effect of mastitis on reproduction and production of lactating dairy cows has
been vastly studied, little information is available about the association of maternal udder …

Neonatal proinflammatory challenge in male Wistar rats: Effects on behavior, synaptic plasticity, and adrenocortical stress response

A Tishkina, M Stepanichev, I Kudryashova… - Behavioural brain …, 2016 - Elsevier
Abstract Effects of neonatal proinflammatory stress (NPS) on the development of anxiety and
depressive-like behavior, stress responsiveness, hippocampal plasticity and conditioned …

Linking stress and infertility: a novel role for ghrelin

L Sominsky, DM Hodgson, EA McLaughlin… - Endocrine …, 2017 - academic.oup.com
Infertility affects a remarkable one in four couples in develo** countries. Psychological
stress is a ubiquitous facet of life, and although stress affects us all at some point, prolonged …

The novel human β-defensin 114 regulates lipopolysaccharide (LPS)-mediated inflammation and protects sperm from motility loss

H Yu, J Dong, Y Gu, H Liu, A **n, H Shi, F Sun… - Journal of Biological …, 2013 - ASBMB
Lipopolysaccharide (LPS) is an important pathological factor involved in serious
inflammatory diseases and male reproductive impairments. Emerging evidence …

Functional programming of the autonomic nervous system by early life immune exposure: implications for anxiety

L Sominsky, EA Fuller, E Bondarenko, LK Ong… - PloS one, 2013 - journals.plos.org
Neonatal exposure of rodents to an immune challenge alters a variety of behavioural and
physiological parameters in adulthood. In particular, neonatal lipopolysaccharide (LPS; 0.05 …

Infection, learning, and memory: Focus on immune activation and aversive conditioning

IR Bishnoi, CJ Cloutier, CD Tyson, VM Matic… - Neuroscience & …, 2022 - Elsevier
Here we review the effects of immune activation primarily via lipopolysaccharide (LPS), a
cell wall component of Gram-negative bacteria, on hippocampal and non-hippocampal …

Neonatal overfeeding induces early decline of the ovarian reserve: implications for the role of leptin

L Sominsky, I Ziko, A Soch, JT Smith… - Molecular and cellular …, 2016 - Elsevier
Early life nutrition is crucial for reproduction. Overweight and obese girls are more likely to
experience early menarche, increasing the risk of adult disease. We have previously …

Impacts of early intervention with fluoxetine following early neonatal immune activation on depression-like behaviors and body weight in mice

MH Doosti, A Bakhtiari, P Zare, M Amani… - Progress in Neuro …, 2013 - Elsevier
Several reports have suggested that early neonatal immune activation adversely influences
the hypothalamic–pituitary–adrenal (HPA) axis development in humans and animal models …