Functional attachment of soft tissues to bone: development, healing, and tissue engineering

HH Lu, S Thomopoulos - Annual review of biomedical …, 2013 - annualreviews.org
Connective tissues such as tendons or ligaments attach to bone across a multitissue
interface with spatial gradients in composition, structure, and mechanical properties. These …

The role of mechanobiology in tendon healing

ML Killian, L Cavinatto, LM Galatz… - Journal of shoulder and …, 2012 - Elsevier
Mechanical cues affect tendon healing, homeostasis, and development in a variety of
settings. Alterations in the mechanical environment are known to result in changes in the …

Finite element analysis of additive manufacturing based on fused deposition modeling: Distortions prediction and comparison with experimental data

A Cattenone, S Morganti… - Journal of …, 2019 - asmedigitalcollection.asme.org
Additive manufacturing (or three-dimensional (3D) printing) is constantly growing as an
innovative process for the production of complex-shape components. Among the seven …

The microstructure and micromechanics of the tendon–bone insertion

L Rossetti, LA Kuntz, E Kunold, J Schock, KW Müller… - Nature materials, 2017 - nature.com
The exceptional mechanical properties of the load-bearing connection of tendon to bone
rely on an intricate interplay of its biomolecular composition, microstructure and …

Mineral distributions at the develo** tendon enthesis

AG Schwartz, JD Pasteris, GM Genin, TL Daulton… - PloS one, 2012 - journals.plos.org
Tendon attaches to bone across a functionally graded interface,“the enthesis”. A gradient of
mineral content is believed to play an important role for dissipation of stress concentrations …

Tendon‐to‐bone attachment: from development to maturity

E Zelzer, E Blitz, ML Killian… - Birth Defects Research …, 2014 - Wiley Online Library
The attachment between tendon and bone occurs across a complex transitional tissue that
minimizes stress concentrations and allows for load transfer between muscles and skeleton …

Enthesis repair: challenges and opportunities for effective tendon-to-bone healing

KA Derwin, LM Galatz, A Ratcliffe, S Thomopoulos - JBJS, 2018 - journals.lww.com
Abstract On May 22, 2017, the National Institutes of Health (NIH)/National Institute of Arthritis
and Musculoskeletal and Skin Diseases (NIAMS) hosted a roundtable on “Innovative …

Biomimetic approaches for the design and fabrication of bone-to-soft tissue interfaces

C Pitta Kruize, S Panahkhahi, NE Putra… - ACS Biomaterials …, 2021 - ACS Publications
Bone-to-soft tissue interfaces are responsible for transferring loads between tissues with
significantly dissimilar material properties. The examples of connective soft tissues are …

Functionally graded adhesives for composite joints

SE Stapleton, AM Waas, SM Arnold - International Journal of Adhesion and …, 2012 - Elsevier
Adhesives with functionally graded material properties are being considered for use in
adhesively bonded joints to reduce the peel stress concentrations located near adherend …

Tough and tunable scaffold-hydrogel composite biomaterial for soft-to-hard musculoskeletal tissue interfaces

RA Sun Han Chang, JF Shanley, ME Kersh… - Science …, 2020 - science.org
Tendon inserts into bone via a fibrocartilaginous interface (enthesis) that reduces
mechanical strain and tissue failure. Despite this toughening mechanism, tears occur …