Prostaglandins (PG) are oxygenated derivatives of C20 polyunsaturated fatty acids including
arachidonic and eicosapentaenoic acids. In mammals, these compounds have been shown …

Prostaglandin G/H synthases (PGHS), commonly referred to as cyclooxygenases (COX-1
and COX-2), catalyze a key step in the synthesis of biologically active prostaglandins (PGs) …

Biological membranes can be protected from lipid peroxidation by antioxidant enzymes
including catalase (CAT) and selenium-dependent glutathione peroxidases 1 and 4 (GPx1 …

The cyclooxygenase (COX) pathway converts arachidonic acid (ArA) into prostaglandins
(PGs), which interact with the stress response in mammals and possibly in fish as well …

The cyclooxygenases (Cox) catalyze the initial reactions in prostanoid biosynthesis, and
produce the common prostanoids precursor, PGH2. Mammalian species have two Cox …

In the kidneys of mammals, cyclooxygenase type 2 (COX2) is expressed in medullary
interstitial cells, the macula densa and epithelial cells of the cortical thick ascending limb …

The mediation of nociception with analgesic medications has not been well documented in
elasmobranchs. The purpose of this study was to determine effective analgesic doses of the …

The fish gut holds special status among internal organs since its lumen is continuous with
the external medium, giving the gut direct contact in a technical sense with the outside world …

Maternal transfer is a notable contaminant source for elasmobranchs during the embryonic
development. The maternal offloading of several compounds has been evaluated …

G protein-coupled receptors (GPCR) are used ubiquitously and widely for signal
transduction across the plasma membrane. The ligands for GPCRs are structurally diverse …