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[HTML][HTML] Polymer based sustained drug delivery to the ocular posterior segment: barriers and future opportunities for the treatment of neovascular pathologies
There is an increasing momentum in research and pharmaceutical industry communities to
design sustained, non-invasive delivery systems to treat chronic neovascular ocular …
design sustained, non-invasive delivery systems to treat chronic neovascular ocular …
[HTML][HTML] Intravitreal therapeutic nanoparticles for age-related macular degeneration: Design principles, progress and opportunities
Age-related macular degeneration (AMD) is a leading cause of vision loss in the elderly. The
current standard treatment for AMD involves frequent intravitreal administrations of …
current standard treatment for AMD involves frequent intravitreal administrations of …
Beyond VEGF: targeting inflammation and other pathways for treatment of retinal disease
Neovascular eye diseases include conditions such as retinopathy of prematurity,
proliferative diabetic retinopathy, and neovascular age-related macular degeneration …
proliferative diabetic retinopathy, and neovascular age-related macular degeneration …
Six-month sustained delivery of anti-VEGF from in-situ forming hydrogel in the suprachoroidal space
Patients with wet age-related macular degeneration (AMD) require intravitreal injections of
bevacizumab (Bev) or other drugs, often on a monthly basis, which is a burden on the …
bevacizumab (Bev) or other drugs, often on a monthly basis, which is a burden on the …
Particle carriers for controlled release of peptides
There has been growing discovery and use of therapeutic peptides in drug delivery and
tissue engineering. Peptides are smaller than proteins and can be formulated into drug …
tissue engineering. Peptides are smaller than proteins and can be formulated into drug …
Fabrication, drug delivery kinetics and cell viability assay of PLGA-coated vancomycin-loaded silicate porous microspheres
Porous ceramic microspheres are a desirable substance for bone tissue reconstruction and
delivery applications. This study focuses on Mg–Ca silicate microspheres encapsulated in …
delivery applications. This study focuses on Mg–Ca silicate microspheres encapsulated in …
Nanomaterials in the diagnosis and treatment of ophthalmic diseases
Y Ma, Z Zhang, Y Yu, X Wang, S Liu, B Sun, Z Cai… - Nano Today, 2024 - Elsevier
The complexity of the human eye structure poses challenges in the diagnosis and treatment
of ocular diseases, especially the low efficiency of ocular drug delivery. With the continuous …
of ocular diseases, especially the low efficiency of ocular drug delivery. With the continuous …
A three-dimensional printed polycaprolactone scaffold combined with co-axially electrospun vancomycin/ceftazidime/bone morphological protein-2 sheath-core …
YH Yu, D Lee, YH Hsu, YC Chou… - International journal …, 2020 - Taylor & Francis
Introduction Masquelet proposed a new solution for the healing of segmental bone defects,
thus minimizing the disadvantages associated with traditional bone grafting. However, a …
thus minimizing the disadvantages associated with traditional bone grafting. However, a …
Enhanced drug carrier capacity after post modification process for amino acid substitute phosphazene based microspheres with anticancer activity
In this study, drug carrier HCCP-PP-LEEMP microspheres were synthesized by using
Hexachlorocyclotriphosphazene (HCCP), Phenolphthalein (PP) and l-Lysine Ethyl Ester …
Hexachlorocyclotriphosphazene (HCCP), Phenolphthalein (PP) and l-Lysine Ethyl Ester …
Recent Advances in Formulations for Long-Acting Delivery of Therapeutic Peptides
P Sahandi Zangabad… - ACS Applied Bio …, 2023 - ACS Publications
Recent preclinical and clinical studies have focused on the active area of therapeutic
peptides due to their high potency, selectivity, and specificity in treating a broad range of …
peptides due to their high potency, selectivity, and specificity in treating a broad range of …